This link has been bookmarked by 257 people and liked by 1 people. It was first bookmarked on 12 May 2008, by B Diettrich.
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sean beaverson@smbeaverson @avantgame Here is the game you are looking for… http://t.co/amII73L4wa
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30 Dec 14
Martin SlavíkFoldit is a revolutionary new computer game enabling you to contribute to important scientific research.
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26 Jul 13
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Figuring out which of the many, many possible structures is the best one is regarded as one of the hardest problems in biology today and current methods take a lot of money and time, even for computers. Foldit attempts to predict the structure of a protein by taking advantage of humans' puzzle-solving intuitions and having people play competitively to fold the best proteins.
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chris deason"Foldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help."
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lamoillegoldFold it
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Tara Slominski"predict the structure of a protein by taking advantage of humans' puzzle-solving intuitions and having people play competitively to fold the best proteins"
biochemistry, cell biology -
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What are amino acids? Amino acids are small molecules made up of atoms of carbon, oxygen, nitrogen, sulfur, and hydrogen. To make a protein, the amino acids are joined in an unbranched chain, like a line of people holding hands. Just as the line of people has their legs and feet "hanging" off the chain, each amino acid has a small group of atoms (called a sidechain) sticking off the main chain (backbone) that connects them all together. There are 20 different kinds of amino acids, which differ from one another based on what atoms are in their sidechains. These 20 amino acids fall into different groups based on their chemical properties: acidic or alkaline, hydrophilic (water-loving) or hydrophobic (greasy).
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- Amylase starts the process of breaking down starch from food into forms the body can use.
- Alcohol dehydrogenase transforms alcohol from beer/wine/liquor into a non-toxic form that the body uses for food.
- Hemoglobin carries oxygen in our blood.
- Fibrin forms a scab to protect cuts as they heal.
- Collagen gives structure and support to our skin, tendons, and even bones.
- Actin is one of the major proteins in our muscles.
- Growth hormone helps regulate the growth of children into adults.
- Potassium channels help send signals through the brain and other nerve cells.
- Insulin regulates the amount of sugar in the blood and is used to treat diabetes.
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25 May 12
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23 May 12
Patti PortoFoldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help.
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28 Mar 12
Jennifer ChoFoldit is a game designed to tackle the problem of protein folding. By learning more about the 3-D structure of proteins (or how they "fold"), scientists can better understand their function, and get a better idea of how to combat diseases, create vaccines and even find novel biofuels. In Foldit, players are presented with a model of a protein, which they can fold by using a variety of provided tools. The game evaluates how well the player has folded the protein and gives them a score. Scores are uploaded to a leader board, allowing for competition between players from all around the world. This is good for high school and college level.
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Wayne HodgkinsonGame (that helps enhance world scientific understanding) by folding proteins / amino acids together.
science Biology game foldit proteins protein folding Education
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Foldit is a revolutionary new computer game enabling you to contribute to important scientific research.
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Foldit attempts to predict the structure of a protein by taking advantage of humans' puzzle-solving intuitions and having people play competitively to fold the best proteins.
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05 Nov 11
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04 Nov 11
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29 Oct 11
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25 Oct 11
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04 Oct 11
Liz BadeFoldit is a revolutionary new computer game enabling you to contribute to important scientific research.
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02 Oct 11
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27 Sep 11
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21 Sep 11
Daniela LuponeFoldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help.
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20 Sep 11
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Proteins are the workhorses in every cell of every living thing. Your body is made up of trillions of cells, of all different kinds: muscle cells, brain cells, blood cells, and more. Inside those cells, proteins are allowing your body to do what it does: break down food to power your muscles, send signals through your brain that control the body, and transport nutrients through your blood.
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Amino acids are small molecules made up of atoms of carbon, oxygen, nitrogen, sulfur, and hydrogen. To make a protein, the amino acids are joined in an unbranched chain, like a line of people holding hands. Just as the line of people has their legs and feet "hanging" off the chain, each amino acid has a small group of atoms (called a sidechain) sticking off the main chain (backbone) that connects them all together. There are 20 different kinds of amino acids, which differ from one another based on what atoms are in their sidechains. These 20 amino acids fall into different groups based on their chemical properties: acidic or alkaline, hydrophilic (water-loving) or hydrophobic (greasy).
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Even though proteins are just a long chain of amino acids, they don't like to stay stretched out in a straight line. The protein folds up to make a compact blob, but as it does, it keeps some amino acids near the center of the blob, and others outside; and it keeps some pairs of amino acids close together and others far apart. Every kind of protein folds up into a very specific shape -- the same shape every time.
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The unique shape of a particular protein is the most stable state it can adopt.
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- Photosystem I is a collection of proteins in plants that captures sunlight for photosynthesis.
- Luciferase catalyzes the chemical reaction that makes fireflies glow.
- Hemagglutinin helps the influenza virus invade our cells.
Some organisms have proteins that give them their special characteristics:
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As described above, knowing the structure of a protein is key to understanding how it works and to targeting it with drugs. A small proteins can consist of 100 amino acids, while some human proteins can be huge (1000 amino acids). The number of different ways even a small protein can fold is astronomical because there are so many degrees of freedom. Figuring out which of the many, many possible structures is the best one is regarded as one of the hardest problems in biology today and current methods take a lot of money and time, even for computers. Foldit attempts to predict the structure of a protein by taking advantage of humans' puzzle-solving intuitions and having people play competitively to fold the best proteins.
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19 Sep 11
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18 Sep 11
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29 Aug 11
John Ross"Foldit is a revolutionary new computer game enabling you to contribute to important scientific research."
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08 Aug 11
Charles van der Haegen"Foldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help.
Page Contents:
What is protein folding?
Why is this game important?
Foldit Scientific Publications
News Articles about Foldit
News Articles about Rosetta
Rosetta@Home Screensaver
What is protein folding?
Folded up Puzzle 48 (+) Enlarge This Image
What is a protein? Proteins are the workhorses in every cell of every living thing. Your body is made up of trillions of cells, of all different kinds: muscle cells, brain cells, blood cells, and more. Inside those cells, proteins are allowing your body to do what it does: break down food to power your muscles, send signals through your brain that control the body, and transport nutrients through your blood. Proteins come in thousands of different varieties, but they all have a lot in common. For instance, they're made of the same stuff: every protein consists of a long chain of joined-together amino acids.
What are amino acids? Amino acids are small molecules made up of atoms of carbon, oxygen, nitrogen, sulfur, and hydrogen. To make a protein, the amino acids are joined in an unbranched chain, like a line of people holding hands. Just as the line of people has their legs and feet "hanging" off the chain, each amino acid has a small group of atoms (called a sidechain) sticking off the main chain (backbone) that connects them all together. There are 20 different kinds of amino acids, which differ from one another based on what atoms are in their sidechains. These 20 amino acids fall into different groups based on their chemical properties: acidic or alkaline, hydrophilic (water-loving) or hydrophobic (greasy)." -
25 Jul 11
josh lambertComputer game that lets the student contribute to scientific research
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Gerald CareyHelp find the cure for many different disease by playing the Foldit game. It's all to do with how proteins fold.
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21 Mar 11
stéphane koch"Foldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help."
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10 Mar 11
Andy PetroskiFoldit is a revolutionary new computer game enabling you to contribute to important scientific research.
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20 Feb 11
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Proteins are the workhorses in every cell of every living thing
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Amino acids are small molecules made up of atoms of carbon, oxygen, nitrogen, sulfur, and hydrogen.
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Every kind of protein folds up into a very specific shape -- the same shape every time. Most proteins do this all by themselves, although some need extra help to fold into the right shape.
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Why is shape important? This structure specifies the function of the protein.
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Perhaps we can find new proteins to do it better.
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15 Feb 11
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31 Jan 11
Sharon Stanski"Foldit is a revolutionary new computer game enabling you to
contribute to important scientific research" -
16 Jan 11
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07 Jan 11
valerie taylorFoldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help.
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04 Dec 10
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Foldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help.
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01 Nov 10
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31 Oct 10
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irene villasenorFoldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help.
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27 Sep 10
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17 Sep 10
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