Scientists say a female's vaginal mucus carrying a specific type of bacteria could be the women’s first line of defence against HIV and other sexually transmitted infections.
“Mucosal surfaces, such as the lung, gastrointestinal tract, or female reproductive tract, are where most infections take place. Our bodies secrete over six liters of mucus every day as a first line of defense,” said Sam Lai, senior author of the study and Assistant Professor of Pharmacy and Engineering at University of North Carolina at Chapel Hill.
How much does it cost to treat breast cancer? No one seems to know.
Uninsured cancer patients pay up to twice as much for doctors’ visits and 43 times as much for chemotherapy drugs compared with what Medicare and private insurance pays, a study from the University of North Carolina at Chapel Hill showed.
“This is unreasonable,” said Stacie Dusetzina, an assistant professor in the Eshelman School of Pharmacy and the Gillings School of Global Public Health. “There needs to be more transparency and less variability in health care pricing.”
Millions of patients get diagnosed and suffer through the long and painful treatment against breast cancer, but until today, no one seems to really know how much it cost to treat the disease.
“This is unreasonable. There needs to be more transparency and less variability in health care pricing.” stated assistant professor Stacie Dusetzina from the Eshelman School of Pharmacy and the Gillings School of Global Public Health.
The emails pour into Elena Batrakova’s computer daily.
Batrakova, a researcher at UNC-Chapel Hill’s Eshelman School of Pharmacy's Center for Nanotechnology in Drug Development, didn’t have a personal stake in Parkinson’s disease, a degenerative neurological disorder. There’s no father, brother, child suffering from the ailment, which can impact everything from motor skills to mental clarity. There's no childhood friend-turned-patient to inspire the mission.
UNC-Chapel Hill announced Wednesday that it has joined an international network mapping targets for cancer drugs.
The 11-year-old global partnership is called the Structural Genomics Consortium. The UNC hub will be the first in the United States. It was created with start-up funding from the UNC Eshelman Institute for Innovation at the Eshelman School of Pharmacy.
In 2010, the Institute for Safe Medication Practices (ISMP) declared the “syringe pull-back” method unsafe for preparing IV medications (ISMP Medication Safety Alert Acute Care 2010;15:13; http://goo.gl/aM0SjO).
The University of North Carolina (UNC) Medical Center, where Lindsey Amerine, PharmD, MS, is the assistant director of pharmacy and an assistant professor of clinical education at UNC Eshelman School of Pharmacy, in Chapel Hill, is one institution that has recently chosen to remove the subjective element from their IV drug preparation process and switch to a commercial IV workflow system that weighs the drug to verify the accuracy of a dose.
As a potential treatment for Parkinson’s disease, scientists at UNC-Chapel Hill have created smarter immune cells that produce and deliver a healing protein to the brain while also teaching neurons to begin making the protein for themselves.
The researchers, led by Elena Batrakova, an associate professor at the UNC Eshelman School of Pharmacy’s Center for Nanotechnology in Drug Delivery, genetically modified white blood cells called macrophages to produce glial cell–derived neurotrophic factor, or GDNF, and deliver it to the brain. Glial cells provide support and protection for nerve cells throughout the brain and body, and GDNF can heal and stimulate the growth of damaged neurons.
Scientists at the University of North Carolina at Chapel Hill may have a breakthrough in the battle against Parkinson’s disease.
UNC scientists have created immune cells that produce and deliver a healing protein to the brain while also teaching neurons to begin making the protein for themselves, UNC said in a news release Thursday.
The researchers, led by Elena Batrakova, an associate professor at the UNC Eshelman School of Pharmacy’s Center for Nanotechnology in Drug Delivery, genetically modified white blood cells called macrophages to produce glial cell-derived neurotrophic factor, or GDNF, and deliver it to the brain, UNC said.
UNC-Chapel Hill officials celebrated their record fundraising year Wednesday with a party and a promise to gear up an expected seven-year campaign.
Buoyed by a $100 million gift announcement from pharmaceutical magnate Fred Eshelman, UNC-Chapel Hill announced 2014-15 as a record fundraising year. In total, UNC received nearly $447 million in commitments, a 44 percent jump from the previous year and beating out the previous record of $343 million, set in 2008, by a wide margin.
Dangerous interactions between prescriptions and foods that are often overlooked.
"On statin medications, it is best to avoid to grapefruit juice completely," says Stefanie Ferreri, a clinical professor at the University of North Carolina Eshelman School of Pharmacy.
Patients diagnosed with cancer will face increasing costs, not only with prices for drugs increasing, but also because insurance companies are increasing out-of-pocket costs.
As patients face these higher costs, doctors are speaking out.
“It is important to remember that patients are dealing with an enormous burden of a cancer diagnosis – asking them to further shoulder huge costs for the treatments that their doctors prescribe is unreasonable,” wrote Stacie Dusetzina, a UNC Lineberger Comprehensive Cancer Center member and an assistant professor in the UNC Eshelman School of Pharmacy. “Making sure that effective treatments are available – at a reasonable cost – to the patients that need them should be a very high priority for us as a society.”
Bad chemical probes have messed up clinical trials for breast cancer...
At the moment the portal is populated with entries for a mere seven probes, notes William Zuercher, a chemical biologist at the University of North Carolina at Chapel Hill, and a co-author on the commentary. The portal has £50,000 (US$78,000) of seed funding from the London-based biomedical charity the Wellcome Trust, and a small group of the co-authors have pledged to curate and enter data on probes. The team hopes to hire someone to lead the project in the next few weeks. The success of the portal will depend on experts turning their frustration with inconclusive work into action, says Zuercher. “To make the resource sustainable, we will need community input.”
At any given time, almost half of all Americans are using at least one prescription drug. That’s not to mention all the over-the-counter medications we take without a prescription. ... Because of these risks, PPIs should be a last resort for heartburn. “The best place to start is by eliminating foods that might trigger the heartburn or by trying an H2 blocker,” says Macary Marciniak, PharmD, a professor at University of North Carolina’s Eshelman School of Pharmacy. H2 blockers, which work in a different way than PPIs, include over-the-counter drugs such as Pepcid and Tagamet....
With the help of a $1.8 million grant, UNC-Chapel Hill will aim to grow the workforce of scientists and doctors working in cancer nanotechnology through the launch of a new postdoctoral training program.
The five-year grant comes from the National Institutes of Health to create a postdoctoral training program within the UNC Eshelman School of Pharmacy’s Center for Nanotechnology in Drug Delivery. The program will be run in collaboration with the Carolina Institute for Nanomedicine, the Carolina Center for Cancer Nanotechnology Excellence and the UNC Lineberger Comprehensive Cancer Center.
Researchers (Shawn Hingtgen) at the University of North Carolina are converting skin cells into stem cells and loading them with anti-cancer drugs to use in the fight against brain tumours. Nathan Frandino reports.
By combining their strengths, three schools of pharmacy in the UK, US and Australia hope to become a voice for change within the pharmacy profession across the world.
For people with advanced diabetes, every day is a balancing act of carefully monitoring their blood sugar and responding by taking insulin through painful injections or cumbersome pumps. New technology under development in the Joint Department of Biomedical Engineering at UNC-Chapel Hill and N.C. State University could render these invasive and imprecise treatments obsolete.
Researchers in North Carolina are developing a "smart" insulin patch that can automatically detect and manage blood sugar levels, an effort they hope might one day make painful, persistent insulin injections obsolete for millions of people with diabetes.