Ledis Leaf's List: arth

• Surgical simulation of nerve compression
• hey over-responded to temperature changes
• animals' gait became asymmetric
• symptoms
• seemed to be linked to an increase in levels of interleukin-17 (IL-17), a protein involved in regulating the inflammatory response. Elevated levels of IL-17 have already been implicated in such autoimmune diseases as rheumatoid arthritis
• dorsal root ganglia in the lumbar region
• placement of more weight on the non-affected limb

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• Osteoarthritis
• vascular cell adhesion molecule 1 (VCAM-1), was a strong predictor of hip and knee joint replacement due to severe OA
• VCAM-1 promotes leukocyte adhesion and homing to
• inflammation
• In chondrocytes (cartilage cells), VCAM-1 expression
• induced by inflammatory
• cytokines

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