4thGeneration Mushfa's List: Disorders & Diseases

• Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease of unknown cause
• disease-modifying antirheumatic drugs (DMARDs) has become the standard of care
• Many of the newer DMARD therapies, however, are
• immunosuppressive in nature
• higher risk for partially masked serious bacterial, and sometimes fungal, infections
• Optimal care of patients with RA requires an integrated approach of pharmacologic and nonpharmacologic therapies

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