You can create some custom perspective in which you explicitly do not activate some plugins
optimizing your eclipse.ini (see this SO answer for that)
Open the Preferences and navigate to General -> Startup and Shutdown
I suggest you fiddle with the Xmx and Xms parameters for eclipse. Giving Eclipse the maximum memory it can take helps a lot. I set Xmx to 1024M for example, but it can go higher (it does have a cap though, but I can't remember what it is)
Another parameter to look at is the launcher.XXMaxPermSize.