Nora Holmes's List: business insider

• breathing difficulties
• malnutrition
• extra bone formation around the rib cag
• Flare-ups may also be caused by viral illnesses
• What genes are related to fibrodysplasia ossificans progressiva?
• ACVR1
• provides instructions for producing a member of a protein family called bone morphogenetic protein
• ACVR1 protein is found in many tissues of the body including skeletal muscle and cartilage
• helps to control the growth and development of the bones and muscles, including the gradual replacement of cartilage by bone
• Researchers believe that a mutation in the ACVR1 gene may change the shape of the receptor
• and disrupt mechanisms that control the receptor's activity.
• the receptor may be constantly turned on
• causes overgrowth of bone and cartilage and fusion of joints
• How do people inherit fibrodysplasia ossificans progressiva?
• one copy of the altered gene in each cell is sufficient to cause the disorder.
• Most cases of fibrodysplasia ossificans progressiva result from new mutations
• small number of cases, an affected person has inherited
• no history of the disorder

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• • 1
    modern problems
    - US decreasing influence in the ME; has a speech
• US influence in the region is at a post-World War II low.
• America is leaving Iraq and Afghanistan.
• we have lost the will
• can't afford such battles
• power to appear tough
• fewer dollars for foreign aid, fewer troops to deploy, and less money to support long supply chains and extended deployments
• relative economic clout of the United States in the region has diminished as markets like China and other rapidly growing economies have become more important in terms of energy consumption.
• relative political clout of the U.S. in the region has shrunk as, in addition to all the above reasons, emerging powers are playing an ever bigger role and are easier, less-demanding partners

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