Figure 21 shows a P-V loop during a mandatory breath in which a decrease in compliance occurs toward the end of inspiration. This is represented by a flattening of the inspiratory curve (A) and is the result of alveolar overdistension. [quiz question on that one] As inspiration proceeds and the alveoli begin to exceed their volume capacity, their compliance begins to decrease, displaying an increase in pressure with little or no corresponding volume increase
We do not want lung overdistension of course, so we would decrease tidal volume here. No more guessing about whether the tidal volume is set too high. We wonder how many patients have been done a disservice when tidal volume was based on height. I even taught that formula for years. But, it was all we knew for quite a while.