We have stained neurons and endothelial cells in human brains by antibodies against cell type-specific marker proteins, isolated the cells using laser capture microdissection, and identified genes preferentially expressed in the two cell types.
We find that genes preferentially expressed in neurons differ less across tissues and developmental stages than genes preferentially expressed in endothelial cells.
We also observe less expression differences within primate species for neuronal transcriptomes.
we see more gene expression differences between humans, chimpanzees, and rhesus macaques relative to within-species differences in genes expressed preferentially in neurons than in genes expressed in endothelial cells. This suggests that neuronal and endothelial transcriptomes evolve at different rates within brain tissue.
The box jellyfish (Tripedelia cystophora), for example, is a fast and active hunter and stalks its prey with the aid of 24 fully functioning eyes. These are grouped into four clusters called rhopalia, which lie on each side of its cube-like body. Together, they give the box jellyfish a complete 360 degree view of its world and make it highly manoeuvrable.
Even though jellyfish are the most ancient group of animals to have a well developed visual system, it turns out that their eyes are built with many of the same genetic building blocks that ours are.