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Weiye Loh's Library tagged Research   View Popular, Search in Google

May
19
2012

if you're a senior scientist wanting to set up a lab in another institution, the first question you're going to ask is whether you're going to have good students (who of course do all the actual lab work). Unfortunately, Singapore seems to do a very good job of exporting its best students. They're sent overseas on fully-funded, prestigious scholarships to foreign institutions.

Science Research Community Singapore Scholarship

  • if you're a senior scientist wanting to set up a lab in another institution, the first question you're going to ask is whether you're going to have good students (who of course do all the actual lab work). Unfortunately, Singapore seems to do a very good job of exporting its best students. They're sent overseas on fully-funded, prestigious scholarships to foreign institutions.
  • If the best students do not stay in the country, then it is difficult to develop local institutions to higher levels. Worse still, we are not building confidence in our own institutions.
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May
12
2012

Bias is an inescapable element of research, especially in fields such as biomedicine that strive to isolate cause–effect relations in complex systems in which relevant variables and phenomena can never be fully identified or characterized. Yet if biases were random, then multiple studies ought to converge on truth. Evidence is mounting that biases are not random. A Comment in Nature in March reported that researchers at Amgen were able to confirm the results of only six of 53 'landmark studies' in preclinical cancer research (C. G. Begley & L. M. Ellis Nature 483, 531–533; 2012). For more than a decade, and with increasing frequency, scientists and journalists have pointed out similar problems.

Science Publication Selection Bias Research Academic Journal Academic Research

  • Bias is an inescapable element of research, especially in fields such as biomedicine that strive to isolate cause–effect relations in complex systems in which relevant variables and phenomena can never be fully identified or characterized. Yet if biases were random, then multiple studies ought to converge on truth. Evidence is mounting that biases are not random. A Comment in Nature in March reported that researchers at Amgen were able to confirm the results of only six of 53 'landmark studies' in preclinical cancer research (C. G. Begley & L. M. Ellis Nature 483, 531–533; 2012). For more than a decade, and with increasing frequency, scientists and journalists have pointed out similar problems.
  • Initially these biases seemed easy to address, and in some ways they offered psychological comfort. The problem, after all, was not with science, but with the poison of the profit motive. It could be countered with strict requirements to disclose conflicts of interest and to report all clinical trials.

     
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Feb
28
2012

Two NGOs for shark conservation, Shark Savers and Project: FIN, protested against Singapore’s unwillingness to ban shark fin products, at the Animal Welfare Symposium last Saturday. 
Project: FIN founder Jennifer Lee quoting a WildAid letter in her question to Minister K Shanmugam and the panel at the end of the symposium, protested against trade interests behind the ‘marine life experts’ Hank Jenkins and Dr. Giam Choo Hoo, exposing their conflicts of interest with wildlife trade.

Sharks Finning Funding Activism Research Sustainability

  • The WildAid letter said: 
     
     
    “Having known Dr. Giam for some time, I don't think he would claim to be a "marine life expert." He is a former vet who was in charge of the bureaucratic aspects of wildlife import and export in Singapore. I believe he still serves on the board of a reptile skin trading company and has served on a CITES committee where he was a tireless advocate against restrictions or controls on trade in threatened and endangered species. 
     
     
     
    "You would need to ask him who pays his expenses and consultancy now. Whenever I’ve asked him, he wouldn't tell.
     
     
     
    "To my knowledge, Dr. Giam has never conducted any original research on sharks of any kind nor has he visited any of the shark fisheries to which he refers. At one point, I offered for my colleague, who had done such research, to make him better informed on sharks, and his response was, "Oh no, she knows too much.
     
     
     
    "Similarly, Hank Jenkins is not a "marine life expert." I believe his expertise is in crocodile farming. He too has been a strong advocate for trade in wildlife and endangered species, such as "farming" tigers.
     
     
     
    They are, of course, like the shark fin traders they represent, entitled to their opinions, but to suggest they are experts in sharks or marine life is misleading.”
  • The main reasons tackling the illegal wildlife trade is ineffective may be due to the fact that the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES), being a political organisation which uses economic trade as a tool to tackle the illegal wildlife trade, has conflicting trade and conservation interests, Professor Oakley noted. 
Feb
14
2012

One of the arguments for special government support of manufacturing is that manufacturing is a key to industrial R&D throughout the US economy (e.g., here). The data above comes from BEA and NSF and shows that as manufacturing declined as a portion of GDP from 2002 to 2007, industry R&D nonetheless increased (note: NSF data goes to 2007).

Manufacturing Industry Research Economics

Does “soft power” matter in international relations? Specifically, when the U.S. seeks cooperation from countries around the world, do the views of their publics about U.S. foreign policy affect the actual foreign policy behavior of these countries? We examine this question using multinational surveys covering 58 countries, combined with information about their foreign policy decisions in 2003, a critical year for the U.S. We draw our basic conceptual framework from Joseph Nye, who uses various indicators of opinion about the U.S. to assess U.S. soft power. But we argue that his theory lacks the specificity needed for falsifiable testing. We refine it by focusing on foreign public opinion about U.S. foreign policy, an under-emphasized element of Nye’s approach. Our regression analysis shows that it has a significant and large effect on troop commitments to the war in Iraq, even after controlling for various hard power factors. It also has significant, albeit small, effects on policies towards the International Criminal Court, and on voting decisions in the U.N. General Assembly. These results support our refined theoretical argument about soft-power: Public opinion about U.S. foreign policy in foreign countries does affect their policies towards the U.S., but this effect is conditional on the salience of an issue for mass publics.

Soft Power Power Foreign Policy Research

Feb
9
2012

On pure vs. applied science: the best research is “pure” research, often with no practical goal in mind.

Science Research Methodology Consequentialism

  • people think that science is about planning your research carefully to achieve some specific goal. They are often not tolerant about “pure research” that doesn’t have a specific conclusion in mind, but is focused on finding out general facts about nature, whether or not they have practical uses. Even the scientific funding agencies operate this way, where they tend to reward research that is conventional and “more of the same,” and seldom fund research that is a speculative gamble.
  • More often than not, scientists who find a crucial new piece of evidence were not looking for it, but looking for something else, and make their great discovery without planning to. The term “serendipity” was describes this phenomenon.
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Dec
22
2011

Two groups of scientists who carried out highly controversial studies with the avian influenza virus H5N1 have reluctantly agreed to strike certain details from manuscripts describing their work after having been asked to do so by a U.S. biosecurity council. The as-yet unpublished papers, which are under review at Nature and Science, will be changed to minimize the risks that they could be misused by would-be bioterrorists.

But the stricken details may still be made available to influenza scientists who have a legitimate interest in knowing them under a new system the journals and U.S. government officials have been actively debating for some time.

The two papers have both been reviewed at length by the U.S. National Science Advisory Board for Biosecurity (NSSAB), and both have been the subject of intense global media attention the past 2 months. They have also triggered debates among scientists, security experts, and officials within various branches of the U.S. government.

Research Publication Selection Censorship Terrorism

Dec
11
2011

At first glance, Robert Kirshner took the e-mail message for a scam. An astronomer at King Abdulaziz University (KAU) in Jeddah, Saudi Arabia, was offering him a contract for an adjunct professorship that would pay $72,000 a year. Kirshner, an astrophysicist at Harvard University, would be expected to supervise a research group at KAU and spend a week or two a year on KAU's campus, but that requirement was flexible, the person making the offer wrote in the e-mail. What Kirshner would be required to do, however, was add King Abdulaziz University as a second affiliation to his name on the Institute for Scientific Information's (ISI's) list of highly cited researchers.

Academia Ranking Research

Oct
12
2011

The idea of reflective equilibrium was introduced by Nelson Goodman in his book “Fact, Fiction, and Forecast.” Goodman was not concerned with morality, but with the validity of one’s thinking. Goodman’s suggestion was that we justify our rules of reasoning based on how those rules fare when confronted with a range of instances of what we believe are correct inferences. If an inferential rule yields unacceptable results, we may decided to discard that rule no matter how it may have seemed like a good idea at the start.

Reflective Equilibrium Philosophy Science Theory Research

  • The most famous application of the principle of reflective equilibrium is found in John Rawls’ highly influential “A Theory of Justice.” Rawls proposed to apply Goodman’s approach to adjusting our sometimes conflicting moral beliefs, just as in the hypothetical case of the Bible and disrespectful children mentioned before. Whether or not one agrees with the outcome of Rawls’ particular analysis of justice as fairness, the reflective equilibrium approach should be compelling to anyone seriously interested in, well, reflecting on her own beliefs.
  • a similar approach had been used in philosophy of science by Pierre Duhem as a way to debunk the commonplace idea that science is about direct empirical testing of theories. Duhem, in a book published in 1908 (La Théorie Physique), pointed out that if there is a disagreement between a theory and the empirical evidence one cannot automatically reject the theory, because scientific theories are complex statements that include many assumptions and sub-theories. The existence of a disagreement between theory and evidence tells us that something is wrong, but not what. It could be that the core theory — say, the Copernican system — ought to be rejected. But it could also be that some adjustment to the theory would resolve the discrepancy (for example, Kepler’s modification of the original Copernicanism to account for the fact that the planets go around following elliptical, not circular orbits). Indeed, it may even be the case that the data is wrong, because of a malfunction of the instrumentation, or an error of interpretation.
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Sep
15
2011

  • I did two wrong and stupid things. The first concerns some people I   interviewed over the years. When I recorded and typed up any conversation, I   found something odd: points that sounded perfectly clear when you heard them   being spoken often don’t translate to the page. They can be quite confusing   and unclear. When this happened, if the interviewee had made a similar point   in their writing (or, much more rarely, when they were speaking to somebody   else), I would use those words instead. At the time, I justified this to   myself by saying I was giving the clearest possible representation of what   the interviewee thought, in their most considered and clear words.
  • But I was wrong. An interview isn’t an X-ray of a person’s finest thoughts.   It’s a report of an encounter. If you want to add material from elsewhere,   there are conventions that let you do that. You write “she has said,”   instead of “she says”. You write “as she told the New York Times” or “as she   says in her book”, instead of just replacing the garbled chunk she said with   the clear chunk she wrote or said elsewhere. If I had asked the many   experienced colleagues I have here at The Independent – who have always been   very generous with their time – they would have told me that, and they would   have explained just how wrong I was. It was arrogant and stupid of me not to   ask.
Sep
7
2011

Ever wondered why we get disgusted by things that taste bad and also by things that are morally outrageous? Well, it seems that they really are connected in a very deep way - moral disgust seems to have evolved as an extension of physical disgust.

And that means you can play a neat trick: you can measure moral disgust indirectly by looking to see how it affects our physical sense of disgust.

Research Methodology Religion Morality

Aug
1
2011

Getting honest answers about behaviour that is illegal or frowned-upon – such as taking drugs or visiting prostitutes – is notoriously difficult. But survey researchers have devised a neat way to get people comfortable with revealing their indiscretions.

Each time the researcher asks the respondent a question, the respondent throws dice before answering – crucially, the researcher cannot see what numbers come up. The rules of the game will be something like this: the respondent will always answer "yes" if they throw a six and "no" when a one comes up, but should tell the truth otherwise.

Because a "yes" doesn't necessarily mean that the respondent actually committed the undesirable behaviour, people seem to open up. The forced "yes" and "no" answers introduce some "noise" into the results, but overall this "randomised response technique" (RRT) gives better answers. For instance, RRT questions get much closer than conventional surveys to the actual incidence of drug use that is revealed by screening tests on hair

Research Methodolatry

Jul
25
2011

When scientists violate moral taboos, we expect horrific consequences. It’s a trope in our storytelling that goes back at least to Mary Shelley’s Frankenstein: However well-intentioned our fictional scientists may be, their disregard for ethical boundaries will produce not a peer-reviewed paper in Science but rather a new race of subhuman killers, a sucking wormhole in space-time, or a profusion of malevolent goo.

In the real world, though, matters aren’t so simple. Most scientists will assure you that ethical rules never hinder good research—that there’s always a virtuous path to testing any important hypothesis. But ask them in private, perhaps after a drink or three, and they’ll confess that the dark side does have its appeal. Bend the rules and some of our deepest scientific conundrums could be elucidated or even resolved: nature versus nurture, the causes of mental illness, even the mystery of how humans evolved from monkeys. These discoveries are just sitting out there, waiting for us to find them, if only we were willing to lose our souls.

What follows are seven creepy experiments—thought experiments, really—that show how contemporary science might advance if it were to toss away the moral compass that guides it. Don’t try these at home—or anywhere, for that matter. But also don’t pretend you wouldn’t like to learn the secrets that these experiments would reveal.

Experiment Research Ethics

Jul
13
2011

you can always “find research to support” anything you like, and I commented to that effect. Indeed, that is exactly how I used to work, before I knew better. Probably until at least 2005, I was still much more of a massage therapist than a science writer. (I quit massage more than a year ago.) I thought like a therapist, had therapist thoughts, and therapist theories. I would bring those ideas to my desk and look for scientific papers in PubMed that backed me up — pretty much the definition of “cherry picking” — and then (groan) fancy myself to be quite the smarty pants. I really hadn’t the faintest clue that scientific papers could be so incredibly misleading, or how trivial a single experimental result was — the sound of one hand clapping.

Research Science Cherry-picking

  • Well-intentioned and naive cherry picking isn’t always a total disaster. If you do it with a shred or two of integrity. You might actually pick some good cherries, and you might care about it when you find one that tastes funny. I started to give less weight to little studies when I noticed that they were often contradicted by better ones. I began to prefer the findings of more credible reviews and larger RCTs.
  • BMJ Clinical Evidence — an excellent organization that publishes EBM reviews (much like the World HQ for EBM, <!-- citekey: cochrane -->The Cochrane Collaboration) — updated their acute low back pain review recently (sorry, link behind paywall — a clever Google search may give you a link that will work from the search results). Here’s what they had to say about spinal manipulative therapy:

     

    One systematic review (149 people) and one subsequent RCT (101 people) added at this update. The review and RCT found no significant difference between spinal manipulation and placebo or usual care in pain. One further study added in harms which reports on adverse effects after spinal manipulation. Categorization of spinal manipulation changed from ‘Likely to be beneficial’ to ‘Unknown effectiveness.’

Jul
10
2011

in the middle of this golden age of behavioral research, there is a bill working through Congress that would eliminate the National Science Foundation’s Directorate for Social, Behavioral and Economic Sciences. This is exactly how budgets should not be balanced — by cutting cheap things that produce enormous future benefits.

Society Social Sciences Funding Academia Research Scarcity Psychology

  • Eldar Shafir of Princeton and Sendhil Mullainathan of Harvard have recently, with federal help, been exploring a third theory, that scarcity produces its own cognitive traits.

     A quick question: What is the starting taxi fare in your city? If you are like most upper-middle-class people, you don’t know. If you are like many struggling people, you do know. Poorer people have to think hard about a million things that affluent people don’t. They have to make complicated trade-offs when buying a carton of milk: If I buy milk, I can’t afford orange juice. They have to decide which utility not to pay.

     These questions impose enormous cognitive demands. The brain has limited capacities. If you increase demands on one sort of question, it performs less well on other sorts of questions.

  • Shafir and Mullainathan gave batteries of tests to Indian sugar farmers. After they sell their harvest, they live in relative prosperity. During this season, the farmers do well on the I.Q. and other tests. But before the harvest, they live amid scarcity and have to think hard about a thousand daily decisions. During these seasons, these same farmers do much worse on the tests. They appear to have lower I.Q.’s. They have more trouble controlling their attention. They are more shortsighted. Scarcity creates its own psychology.
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Jun
22
2011

  • What are the most important lessons you’ve learned about using social media for teaching and outreach?

     

    It is easier to reach fame than impact. If it’s so personal, you run the risk of standing in the way of your content.

  • What’s the single most important piece of advice you would give to someone just starting out in university-level teaching?
     

    Pick the subjects and courses that really interest you rather than those that are predicted to give you nice job and salary, but study what you study very hard and go deeper and broader than what is required.

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Jun
21
2011

Data is everywhere, but use of data is not. So many of our efforts are centered around making money or getting people to buy more things, and this is understandable; however, there are neglected areas that could actually have a huge impact on the way we live. Jake Porway, a data scientist at The New York Times, has a proposition for you, tentatively called Data Without Borders.
[T]here are lots of NGOs and non-profits out there doing wonderful things for the world, from rehabilitating criminals, to battling hunger, to providing clean drinking water. However, they’re increasingly finding themselves with more and more data about their practices, their clients, and their missions that they don’t have the resources or budgets to analyze. At the same time, the data/dev communities love hacking together weekend projects where we play with new datasets or build helpful scripts, but they usually just culminate in a blog post or some Twitter buzz. Wouldn’t it be rad if we could get these two sides together?

Data Open Source Collaboration NGO Research Methodology

Jun
10
2011

It was 1946 and orphans in Guatemala City, along with prisoners, military conscripts and prostitutes, had been selected for a medical experiment which would torment many, and remain secret, for more than six decades.

The US, worried about GIs returning home with sexual diseases, infected an estimated 1,500 Guatemalans with syphilis, gonorrhea and chancroid to test an early antibiotic, penicillin.

Research Ethics Academic Research

  • The US government admitted to the experiment in October when the secretary of state, Hillary Clinton, and the health secretary, Kathleen Sebelius, issued a joint statement apologising for "such reprehensible research" under the guise of public health. Barack Obama phoned his Guatemalan counterpart, Alvaro Colom, to say sorry too.

    Susan Reverby, a professor at Wellesley College in the US, uncovered the experiment while researching the Tuskegee syphilis study in which hundreds of African American men were left untreated for 40 years from the 1930s.

    The Guatemalan study went further by deliberately infecting its subjects. Not only did it violate the hippocratic oath to do no harm but it echoed Nazi crimes exposed around the same time at the Nuremberg trials.

  • More than half of the subjects were low-ranking soldiers delivered by their superiors to US physicians working from a military base in the capital. The Americans initially arranged for infected prostitutes to have sex with prisoners before discovering it was more "efficient" to inject soldiers, psychiatric patients and orphans with the bacterium.
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May
29
2011

Information is more easily accessible now than ever before, and smart, motivated people can sidestep traditional routes to obtain knowledge and disseminate it.

Information Internet Education Knowledge Censorship Research

  • I got an email from a science teacher about a 13-year-old pupil. Both have to remain anonymous. This pupil wrote an article about Brain Gym for her school paper, explaining why it's nonsense: the essay is respectful, straightforward, and factual. But the school decided they couldn't print it, because it would offend teachers in the junior school who use Brain Gym.
    Now, this is weakminded, and perhaps even vicious. More interesting, though, is how often children are able to spot bullshit, and how often adults want to shut them up.
  • Emily Rosa is the youngest person ever to have published a scientific paper in JAMA , one of the most influential medical journals in the world. At the age of nine she saw a TV programme about nurses who practise "Therapeutic Touch", claiming they can detect and manipulate a "human energy field" by hovering their hands above a patient.
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