Alkaptonuria -- GeneReviews -- NCBI Bookshelf
Alkaptonuria is caused by deficiency of homogentisate 1,2-dioxygenase, an enzyme that converts homogentisic acid (HGA) to maleylacetoacetic acid in the tyrosine degradation pathway. The three major features of alkaptonuria are the presence of HGA in the urine, ochronosis (bluish-black pigmentation in connective tissue), and arthritis of the spine and larger joints. Oxidation of the HGA excreted in the urine produces a melanin-like product and causes the urine to turn dark upon standing.
more fromwww.ncbi.nlm.nih.gov
Jason Wolfe's ATLS Page
walk through ATLS - a bit dated (don't give 2l fluid stat) but covers main aspects.
more fromwww.wolfescape.com
The nasopharyngeal airway: dispelling myths and establishing the facts -- Roberts et al. 22 (6): 394 -- Emergency Medicine Journal
more fromemj.bmj.com
Screening Tests APTT
explains why anti-phospholipid antibodies increase APTT in vitro, but are thrombophilic in vivo
more frompractical-hemostasis.com
Because buying new running shoes is more fun than actually running | 43 Folders
more fromwww.43folders.com
Clonic Seizures | epilepsy.com
Major groupings of epilepsy, and types of seizure. "A factor distinguishing clonic from tonic-clonic seizures is that clonic seizures are not followed by a period of tiredness or confusion. Tonic-clonic seizures usually are."
more fromwww.epilepsy.com
Risk of epilepsy after febrile convulsions: a national cohort study.
early 90s: "The risk of epilepsy after febrile convulsions is much less than reported in many hospital studies, and if febrile convulsions cause brain damage that leads to later epilepsy this is a rare occurrence."
more fromwww.pubmedcentral.nih.gov
Wired News - AP News
"It was just of a kid in Romania and how his life is. You can never make a serious documentary if you always have to think about what Flickr will delete."
more fromnews.wired.com
Fresh trouble for NHS IT system | Technology | The Guardian
Last summer, even the outgoing director-general of NHS IT, Richard Granger, admitted: "It really isn't usable because they have been building a system ... without listening to what the end users want."
more fromwww.guardian.co.uk
NHS Cervical Screening Programme
NHS Cervical Screening Programme, public info
more fromwww.cancerscreening.nhs.uk
Bad Science » Screen test
Screening is a fascinating area, mainly because of the maths of rare events, but also because of the ethics.
more fromwww.badscience.net
The screening industry -- Smith 326 (7395): -- BMJ
comment on low effectiveness of cervical screening
more fromwww.bmj.com
cold hearted beasts that they arePrime minister promises raft of new screening tests -- White 336 (7635): 62 -- BMJ
details of Gordon Brown's screening fantasy
more fromwww.bmj.com
Ladas and MOTs -- Spence 336 (7636): 160 -- BMJ
Response to Gordon Brown's ill-considered screening idea
more fromwww.bmj.com
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