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Dr. Essi Viding of the London Kings College Institute of Psychiatry and colleagues have found the tendency toward psychopathic behavior has a strong genetic component.
in list: Neuroethics
Psychopathic killers are the basis for some must-watch TV, but what really makes them tick? Neuroscientist Jim Fallon talks about brain scans and genetic analysis that may uncover the rotten wiring in the nature (and nurture) of murderers. In a too-strange-for-fiction twist, he shares a fascinating family history that makes his work chillingly personal.
in list: Neuroethics
To our knowledge, these findings provide the first evidence for a structural brain deficit in APD. This prefrontal structural deficit may underlie the low arousal, poor fear conditioning, lack of conscience, and decision-making deficits that have been found to characterize antisocial, psychopathic behavior.
in list: Neuroethics
The aim of this investigation was to identify neural systems supporting the processing of intentional and unintentional transgressions of social norms. Using event-related fMRI, we addressed this question by comparing neural responses to stories describing normal behaviour, embarrassing situations or violations of social norms. Processing transgressions of social norms involved systems previously reported to play a role in representing the mental states of others, namely medial prefrontal and temporal regions. In addition, the processing of transgressions of social norms involved systems previously found to respond to aversive emotional expressions (in particular angry expressions); namely lateral orbitofrontal cortex (Brodmann area 47) and medial prefrontal cortex. The observed responses were similar for both intentional and unintentional social norm violations, albeit more pronounced for the intentional norm violations. These data suggest that social behavioural problems in patients with frontal lobe lesions or fronto-temporal dementia may be a consequence of dysfunction within the systems identified in light of their possible role in processing whether particular social behaviours are, or are not, appropriate.
in list: Neuroethics
in list: Neuroethics
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In the “old” or traditional view, psychopathy is seen as a unitary construct that is discrete and qualitatively different from nonpsychopathy. One either is or is not a psychopath.
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a single-gene etiology (causal development) without too much influence from the environment
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in list: Neuroethics
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Psychologists estimate that one in every 100 people is unfeeling enough to qualify as a psychopath, with an especially heavy concentration among criminals.
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A psychological test designed to detect unconscious or frowned-upon attitudes picked up a decided tendency among psychopathic murderers to have abnormally positive attitudes toward violence
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"Neuroscience and neuroimaging is going to change the whole philosophy about how we punish and how we decide who to incapacitate and how we decide how to deal with people," he says, echoing comments of a growing number of leading scholars across the country, including Princeton and Harvard.
in list: Neuroethics
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the Hare Psychopathy Checklist, which measures traits such as the inability to feel empathy or remorse, pathological lying, or impulsivity
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"The scores range from zero to 40," Kiehl explains in his sunny office overlooking a golf course. "The average person in the community, a male, will score about 4 or 5. Your average inmate will score about 22. An individual with psychopathy is typically described as 30 or above. Brian scored 38.5 basically. He was in the 99th percentile."
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psychopaths and various trolley experiments are giving us new insight into the emotional mess of moral decision-making.
in list: Neuroethics
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Psychopathic patients show severe deficits in responding adequately to other people's emotion.
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The results emphasize that although psychopathic patients show no deficits in reasoning about other people's emotion if an explicit evaluation is demanded, they use divergent neural processing strategies that are related to more rational, outcome-oriented processes.
The results emphasize that although psychopathic patients show no deficits in reasoning about other people's emotion if an explicit evaluation is demanded, they use divergent neural processing strategies that are related to more rational, outcome-oriented processes.
in list: Neuroethics
The idea that psychopathy can be identified in childhood is a controversial and sensitive issue.
in list: Neuroethics
affective priming is greatly reduced in callous people who score high on psychopathy.
in list: Neuroethics
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affective priming is greatly reduced in callous people who score high on psychopathy.
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psychopaths show reduced affective priming because positive and negative words don’t trigger activity in their brains’ fear and reward hub, the amygdala, in the same way as happens in healthy people
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"So what is it that makes criminal psychopaths get into trouble, while non-criminal psychopaths do not? The researchers speculated that criminal psychopaths may be steered towards criminality by their backgrounds, in particular a lack of early parental supervision, deprivation and having a convicted parent." (BPS RESEARCH DIGEST)
in list: Neuroethics
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One hundred university students completed a self-report measure of psychopathy that probed four key areas - lack of empathy, grandiosity, impulsivity and delinquency. The top 33 per cent and bottom 33 per cent of scorers subsequently formed high and low psychopathy groups.
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The high psychopathy students, as well as recording low empathy on the self-report test, also scored poorly on the Iowa Card Gambling task (relative to the low psychopathy students), reflecting the same kind of performance seen in criminal psychopaths.
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The brains of psychopaths appear to be wired to keep seeking a reward at any cost, new research from Vanderbilt University finds. The research uncovers the role of the brain's reward system in psychopathy and opens a new area of study for understanding what drives these individuals.
in list: Neuroethics
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"We found that a hyper-reactive dopamine reward system may be the foundation for some of the most problematic behaviors associated with psychopathy, such as violent crime, recidivism and substance abuse."
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impulsivity, heightened attraction to rewards and risk taking
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Few psychological concepts evoke simultaneously as much fascination and misunderstanding as psychopathic personality, or psychopathy. Typically, individuals with psychopathy are misconceived as fundamentally different from the rest of humanity and as inalterably dangerous. Popular portrayals of “psychopaths” are diverse and conflicting, ranging from uncommonly impulsive and violent criminal offenders to corporate figures who callously and skillfully manuever their way to the highest rungs of the social ladder.
in list: Neuroethics
This new, comprehensive review summarizes what is known about psychopathy from psychological science. While contemporary measures of psychopathy have brought much-needed organization to what was once a confused field, there remains debate as to whether psychopathy is a unitary syndrome or a configuration of several different but intersecting traits. The authors propose a new model, drawing on commonalities found among the many diverging definitions of psychopathy, that can serve as a building block for the conceptualization of the disorder. They examine research calling into question the common belief that psychopaths are “born”—rather than being a product of both genetic and environmental influences—and question whether the diagnosis is useful or appropriate for children. They also discuss evidence that, contrary to popular belief, psychopathy is not necessarily linked to violent behavior and that psychopaths are in no way “untreatable.”
in list: Neuroethics
scientific research suggests that psychopathy is a personality disorder that is widely misunderstood.
in list: Neuroethics
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"Psychopathy has long been assumed to be a single personality disorder. However, there is increasing evidence that it is a confluence of several different personality traits,"
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a complex, multifaceted condition marked by blends of personality traits reflecting differing levels of disinhibition, boldness, and meanness.
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Researchers studying the genetic roots of antisocial behavior report that children with one variant of a serotonin transporter gene are more likely to exhibit psychopathic traits if they also grow up poor.
in list: Neuroethics
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children with one variant of a serotonin transporter gene are more likely to exhibit psychopathic traits if they also grow up poor
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more callous and unemotional than their peers
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Psychopaths can be paradox. Some, like Bundy, are intellectually high functioning, and they clearly know right from wrong. They are not delusional, but they are socially inept. They seem to lack normal self-control, and they persistently violate social, legal and moral rules. They don't -- as Bundy's words suggest -- comprehend the human social contract.
in list: Neuroethics
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"I didn't know what made things tick. I didn't know what made people want to be friends. I didn't know what made people attractive to one another. I didn't know what underlay social interaction."
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know right from wrong
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