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Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review1,3.
Hunter JE, Zhang J, Kris-Etherton PM.
Am J Clin Nutr. 2009 Nov 25. [Epub ahead of print]
PMID: 19939984
doi:10.3945/ajcn.2009.27661

Conclusions: TFA intake should be reduced as much as possible because of its adverse effects on lipids and lipoproteins. The replacement of TFA with STA compared with other saturated fatty acids in foods that require solid fats beneficially affects LDL cholesterol, the primary target for CVD risk reduction; unsaturated fats are preferred for liquid fat applications. Research is needed to evaluate the effects of STA on emerging CVD risk markers such as fibrinogen and to understand the responses in different populations.

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2009 November ajcn study review humans dietary stearic_acid STA srfa transfat TFA unsaturated UFA LDL lipoprotein(a) nutrition fibrinogen CVD risk CVD_risk Lp(a) systematic medline risk_factors cholesterol

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs.
Sun Y, Xun K, Wang Y, Chen X.
Anticancer Drugs. 2009 Oct;20(9):757-69.
PMID: 19704371

journals.lww.com/...e_anticancer_properties.1.aspx - Preview

2009 October study systematic review berberine herbs anti-cancer properties nutrition TCM COX-2 inhibitor NF-kappaB growth-inhibitory anti-metastatic metastasis cam altmed medline

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs.
Sun Y, Xun K, Wang Y, Chen X.
Anticancer Drugs. 2009 Oct;20(9):757-69.
PMID: 19704371

journals.lww.com/...articleviewer.aspx - Preview

2009 October study systematic review berberine Chinese herb herbs anti-cancer properties cancer nutrtion Heliobacter_pylori Heliobacter COX-2 inhibitor hepatitis_B

A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
Mente A, de Koning L, Shannon HS, Anand SS.
Arch Intern Med. 2009 Apr 13;169(7):659-69. Review.
PMID: 19364995

Conclusions The evidence supports a valid association of a limited number of dietary factors and dietary patterns with CHD. Future evaluation of dietary patterns, including their nutrient and food components, in cohort studies and randomized trials is recommended

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2009 April archinte study systematic review humans evidence supporting causal link dietary factors CVD CHD nutrition causation vegetables nuts Mediterranean diet Mediterranean_diet pattern fish omega-3 medline

Effects of vitamin D supplementation on strength, physical performance, and falls in older persons: a systematic review.
Latham NK, Anderson CS, Reid IR.
J Am Geriatr Soc. 2003 Sep;51(9):1219-26. Review.
PMID: 12919233
DOI: 10.1046/j.1532-5415.2003.51405.

Conclusion: Although there is insufficient evidence that vitamin D supplementation alone improves physical performance in older people, some data suggest a benefit from vitamin D combined with calcium supplementation, but this requires confirmation in large, well-designed trials.

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2003 September study systematic review humans elderly older old vitamin_D supplementation muscle strength falls muscle_strength physical function performance physical_performance

Dietary protein and bone health: a systematic review and meta-analysis.
Darling AL, Millward DJ, Torgerson DJ, Hewitt CE, Lanham-New SA.
Am J Clin Nutr. 2009 Nov 4. [Epub ahead of print]
PMID: 19889822

www.ajcn.org/...1674 - Preview

2009 November ajcn study research systematic review meta-analysis Dietary protein bone health bone_health BMD osteoporosis nutrition medline

Vitamin D and cognitive performance in adults: a systematic review.
Annweiler C, Allali G, Allain P, Bridenbaugh S, Schott AM, Kressig RW, Beauchet O.
Eur J Neurol. 2009 Oct;16(10):1083-9. Epub 2009 Jul 29.
PMID: 19659751
DOI: 10.1111/j.1468-1331.2009.02755.x

This systematic review shows that the association between serum 25OHD concentrations and cognitive performance is not yet clearly established. The inconclusive results of the reviewed studies could be due to methodology, types of the cognitive tasks used and/or the cellular mechanisms of vitamin D.

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2009 October study systematic review humans adults vvitamin_D nutrition cognition cognitive performance cognitive_performance aging ageing 25ohd memory medline

Vitamin D-Related Changes in Physical Performance: A Systematic Review.
Annweiler C, Schott AM, Berrut G, Fantino B, Beauchet O.
J Nutr Health Aging. 2009;13(10):893-898.
PMID: 19924350

Conclusions: The findings show that the association between vitamin D and physical performance remains controversial. Observational studies and clinical trials yielded divergent results, which highlights the complex and to date still poorly understood association between serum vitamin D concentration or vitamin D supplementation and physical performance.

www.ncbi.nlm.nih.gov/...19924350 - Preview

2009 November study Systematic Review humans Vitamin_D-Related Changes Physical Performance Physical_Performance vitamin_D muscle strength muscle_strength nutrition medline

Effects of n-3 long-chain polyunsaturated fatty acids on depressed mood: systematic review of published trials.
Appleton KM, Hayward RC, Gunnell D, Peters TJ, Rogers PJ, Kessler D, Ness AR.
Am J Clin Nutr. 2006 Dec;84(6):1308-16. Review.
PMID: 17158410

Conclusions: Trial evidence that examines the effects of n–3 PUFAs on depressed mood is limited and is difficult to summarize and evaluate because of considerable heterogeneity. The evidence available provides little support for the use of n–3 PUFAs to improve depressed mood. Larger trials with adequate power to detect clinically important benefits are required.

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2006 December ajcn study systematic review meta-analysis clinical_trials rcts humans omega-3 PUFA PUFAs nutrition medline depression depressed mood

The Health Services Technology/Assessment Texts (HSTAT) is a free, Web-based resource of full-text documents that provide health information and support health care decision making. HSTAT's audience includes health care providers, health service researchers, policy makers, payers, consumers and the information professionals who serve these groups.

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HSTAT Health Services_Technology Assessment Text texts summaries consumer guides reference technical reviews systematic AHRQ Evidence Reports books nutrition directory list NIH NLM NVBI government USA

Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis.
Avenell A, Gillespie WJ, Gillespie LD, O'Connell D.
Cochrane Database Syst Rev. 2009 Apr 15;(2):CD000227. Review.
PMID: 19370554
DOI: 10.1002/14651858.CD000227.pub3

AUTHORS' CONCLUSIONS: Frail older people confined to institutions may sustain fewer hip fractures if given vitamin D with calcium. Vitamin D alone is unlikely to prevent fracture. Overall there is a small but significant increase in gastrointestinal symptoms and renal disease associated with vitamin D or its analogues. Calcitriol is associated with an increased incidence of hypercalcaemia.

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2009 April Cochrane Database study systematic review vitamin_D bone fracture fractures prevention involutional post-menopausal osteoporosis adverse effects nutrition medline

Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
Cockayne S, Adamson J, Lanham-New S, Shearer MJ, Gilbody S, Torgerson DJ.
Arch Intern Med. 2006 Jun 26;166(12):1256-61. Review.
PMID: 16801507

Conclusions This systematic review suggests that supplementation with phytonadione and menaquinone-4 reduces bone loss. In the case of the latter, there is a strong effect on incident fractures among Japanese patients.

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2006 June archinte study review humans systematic meta-analysis clinical_trials rcts vitamin_K vitamin_K1 vitamin_K2 bone fractures fracture prevention supplementation nutrition MK-4 vitamin_K3 medline phytonadione menaquinone-4 osteoporosis

Sunlight, vitamin D and the prevention of cancer: a systematic review of epidemiological studies.
Rhee HV, Coebergh JW, Vries ED.
Eur J Cancer Prev. 2009 Aug 26. [Epub ahead of print]
PMID: 19730382

We, therefore, conclude that there is accumulating evidence for sunlight as a protective factor for several types of cancer. The same conclusion can be made concerning high vitamin D levels and the risk of colorectal cancer. This evidence, however, is not conclusive, because the number of (good quality) studies is still limited and publication biases cannot be excluded. The discrepancies between the epidemiological evidence for a possible preventive effect of sunlight and vitamin D and the question of how to apply the findings on the beneficial effects of sunlight to (public) health recommendations are discussed.

www.ncbi.nlm.nih.gov/...19730382 - Preview

2009 August study review systematic vitamin_D 25ohd sunlight sun exposure cancer prevention cancer_prevention UVB epidemiological studies nutrition medline

Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.
Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B.
JAMA. 2005 May 11;293(18):2257-64. Review.
PMID: 15886381

Conclusions Oral vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons. An oral vitamin D dose of 400 IU/d is not sufficient for fracture prevention.

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2005 May JAMA study review systematic meta-analysis humans clinical_trials rcts Bischoff-Ferrari Willett Giovannucci vitamin_D nonvertebral fracture prevention fractures hip bone osteoporosis nutrition medline elderly old older

The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis.
Pittas AG, Lau J, Hu FB, Dawson-Hughes B.
J Clin Endocrinol Metab. 2007 Jun;92(6):2017-29. Epub 2007 Mar 27. Review.
PMID: 17389701

.CONCLUSIONS: Vitamin D and calcium insufficiency may negatively influence glycemia, whereas combined supplementation with both nutrients may be beneficial in optimizing glucose metabolism.

jcem.endojournals.org/...2017 - Preview

2007 June study review systematic meta-analysis humans vitamin_D calcium role type_2 diabetes nutrition medline insufficiency deficiency glycemia glucose metabolism

Our findings suggest that administration of n-3 FA (EPA and DHA) in doses of at least 1.5 g/day for a prolonged period of time to patients with advanced cancer is associated with an improvement in clinical, biological and QoL parameters.

N-3 fatty acids, cancer and cachexia: a systematic review of the literature.
Colomer R, Moreno-Nogueira JM, García-Luna PP, García-Peris P, García-de-Lorenzo A, Zarazaga A, Quecedo L, del Llano J, Usán L, Casimiro C.
Br J Nutr. 2007 May;97(5):823-31. Review.
PMID: 17408522
doi:10.1017/S000711450765795X

journals.cambridge.org/...displayFulltext - Preview

2007 May bjn study systematic review omega-3 EPA DHA cancer cachexia cancer_cachexia advanced QoL nutrition medline

A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
Mente A, de Koning L, Shannon HS, Anand SS.
Arch Intern Med. 2009 Apr 13;169(7):659-69.
PMID: 19364995

archinte.ama-assn.org/...659 - Preview

2009 April study review systematic CVD CHD risk CHD_risk CVD_risk vegetables nuts Mediterranean diet Mediterranean_diet trans-fat high glycemic_index GI glycemic_load MUFA fish omega-3 folate whole_grains alcohol fruit fiber nutrition medline

Is regular exercise a friend or foe of the aging immune system? A systematic review.
Haaland DA, Sabljic TF, Baribeau DA, Mukovozov IM, Hart LE.
Clin J Sport Med. 2008 Nov;18(6):539-48. Review.
PMID: 19001887
doi: 10.1097/JSM.0b013e3181865eec

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2008 November study review systematic humans elderly older old regular exercise physical_activity friend foe aging immune system immune_system immunity medline health

Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials.
Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C
Int J Cancer. 2008 Sep 15;123(6):1227-39. Review.
PMID: 18623084

www3.interscience.wiley.com/...abstract - Preview

2008 September cancer study review systematic humans altmed cam chemotherapy toxicity efficacy antioxidants nutrtion medline glutathione melatonin vitamin_A N-acetylcysteine selenium vitamin_E L-carnitine ellagic_acid Coenzyme_Q10 Block

Herbs for serum cholesterol reduction: a systematic view.
Thompson Coon JS, Ernst E.
J Fam Pract. 2003 Jun;52(6):468-78. Review.
PMID: 12791229

www.jfponline.com/Pages.asp - Preview

2003 June study review systematic herbs cholesterol reduction cholesterol_reduction hypercholesterolemia high_cholesterol medline altmed cam