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Serum Long-Chain n-3 Polyunsaturated Fatty Acids and Risk of Hospital Diagnosis of Atrial Fibrillation in Men -- Virtanen et al. 120 (23): 2315 -- Circulation
Serum Long-Chain n-3 Polyunsaturated Fatty Acids and Risk of Hospital Diagnosis of Atrial Fibrillation in Men.
Virtanen JK, Mursu J, Voutilainen S, Tuomainen TP.
Circulation. 2009 Dec 8;120(23):2315-21. Epub 2009 Nov 23.
PMID: 19933935
doi: 10.1161/CIRCULATIONAHA.109.852657
Conclusions— An increased concentration of long-chain n-3 PUFAs in serum, a marker of fish or fish oil consumption, may protect against AF. Serum docosahexaenoic acid concentration had the greatest impact.
Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers. - [Psychiatry Res. 2007] - PubMed result
Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers.
Conklin SM, Harris JI, Manuck SB, Yao JK, Hibbeln JR, Muldoon MF.
Psychiatry Res. 2007 Jul 30;152(1):1-10. Epub 2007 Mar 23.PMID: 17383013
Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women -- Richards et al. 86 (5): 1420 -- American Journal of Clinical Nutrition
Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women.
Richards JB, Valdes AM, Gardner JP, Paximadas D, Kimura M, Nessa A, Lu X, Surdulescu GL, Swaminathan R, Spector TD, Aviv A.
Am J Clin Nutr. 2007 Nov;86(5):1420-5.
PMID: 17991655
Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol
Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol.
Glendenning P, Chew GT, Seymour HM, Gillett MJ, Goldswain PR, Inderjeeth CA, Vasikaran SD, Taranto M, Musk AA, Fraser WD.
Bone. 2009 Nov;45(5):870-5. Epub 2009 Jul 23.
PMID: 19631774
doi:10.1016/j.bone.2009.07.015
Cholecalciferol supplementation resulted in a 31% greater increase in total HPLC-measured 25OHD (p=0.010) and 52% greater rise in RIA-measured 25OHD (p<0.001) than supplementation with an equivalent dose of ergocalciferol. Changes in iPTH and wPTH were not significantly different between calciferol treatments (p>0.05). In vitamin D-insufficient hip fracture patients, supplementation with cholecalciferol 1000 IU/day for three months was more effective in increasing serum 25OHD than an equivalent dose of ergocalciferol. However, the lack of difference in PTH lowering between calciferol treatments raises questions about the biological importance of this observation.
Optimal Serum 25-Hydroxyvitamin D Levels for Multiple Health Outcomes - SpringerLink - Book Chapter
Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes.
Bischoff-Ferrari HA.
Adv Exp Med Biol. 2008;624:55-71. Review.
PMID: 18348447
DOI: 10.1007/978-0-387-77574-6_5
Recent evidence suggests that higher vitamin D intakes beyond current recommendations may be associated with better health outcomes. In this chapter, evidence is summarized from different studies that evaluate threshold levels for serum 25(OH)D levels in relation to bone mineral density (BMD), lower extremity function, dental health, risk of falls, admission to nursing home, fractures, cancer prevention and incident hypertension. For all endpoints, the most advantageous serum levels for 25(OH)D appeared to be at least 75 nmol/l (30 ng/ml) and for cancer prevention, desirable 25(OH)D levels are between 90–120 nmol/l (36–48 ng/ml). An intake of no less than 1000IU (25 meg) of vitamin D3 (cholecalciferol) per day for all adults may bring at least 50% of the population up to 75 nmol/l. Thus, higher doses of vitamin D are needed to bring most individuals into the desired range. While estimates suggest that 2000 IU vitamin D3 per day may successfully and safely achieve this goal, the implications of 2000 IU or higher doses for the total adult population need to be addressed in future studies.
Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. - [Lancet. 1989] - PubMed Result
Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study.
Garland CF, Comstock GW, Garland FC, Helsing KJ, Shaw EK, Gorham ED.
Lancet. 1989 Nov 18;2(8673):1176-8.
PMID: 2572900
Blood samples taken in 1974 in Washington County, Maryland, from 25 620 volunteers were used to investigate the relation of serum 25-hydroxyvitamin D (25-OHD) with subsequent risk of getting colon cancer. 34 cases of colon cancer diagnosed between August, 1975, and January, 1983, were matched to 67 controls by age, race, sex, and month blood was taken. Risk of colon cancer was reduced by 75% in the third quintile (27-32 ng/ml) and by 80% in the fourth quintile (33-41 ng/ml) of serum 25-OHD. Risk of getting colon cancer decreased three-fold in people with a serum 25-OHD concentration of 20 ng/ml or more. The results are consistent with a protective effect of serum 25-OHD on colon cancer.
Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarians: the Adventist Health Study-2 -- Chan et al. 89 (5): 1686S -- American Journal of Clinical Nutrition
Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarians: the Adventist Health Study-2.
Chan J, Jaceldo-Siegl K, Fraser GE.
Am J Clin Nutr. 2009 May;89(5):1686S-1692S. Epub 2009 Apr 1.
PMID: 19339396
Conclusions: s25(OH)D concentrations were not associated with vegetarian status. Other factors, such as vitamin D supplementation, degree of skin pigmentation, and amount and intensity of sun exposure have greater influence on s25(OH)D than does diet.
Association between serum 25(OH)D concentrations and bone stress fractures in Finnish young men. - JBMR Online - Journal of Bone and Mineral Research - 21(9):1483 - Full Text
Association between serum 25(OH)D concentrations and bone stress fractures in Finnish young men.
Ruohola JP, Laaksi I, Ylikomi T, Haataja R, Mattila VM, Sahi T, Tuohimaa P, Pihlajamäki H.
J Bone Miner Res. 2006 Sep;21(9):1483-8.
doi: 10.1359/jbmr.060607
Conclusions: A lower level of serum 25(OH)D concentration may be a generally predisposing element for bone stress fractures. Considering the obvious need of additional vitamin D in prevention of stress fractures, the effects of vitamin D fortification of foods and supplementation will be subjects of interest for future research
PMID: 16939407
Low serum 25-hydroxyvitamin D concentrations and secondary hyperparathyroidism in middle-aged white strict vegetarians -- Lamberg-Allardt et al. 58 (5): 684 -- American Journal of Clinical Nutrition
Low serum 25-hydroxyvitamin D concentrations and secondary hyperparathyroidism in middle-aged white strict vegetarians.
Lamberg-Allardt C, Kärkkäinen M, Seppänen R, Biström H.
Am J Clin Nutr. 1993 Nov;58(5):684-9.
PMID: 8237875
In conclusion, white strict vegetarians are at risk of vitamin D deficiency, at least in the winter, primarily because of a low dietary vitamin D intake, despite a normal sunlight exposure in summer. Low serum 25(OH)D concentrations are accompanied by high S-iPTH concentrations, which also are affected by a low calcium intake. The effect of these changes on bone health remains to be evaluated.
Strategies to Improve Vitamin D Status in Northern European Children: Exploring the Merits of Vitamin D Fortification and Supplementation -- Tylavsky et al. 136 (4): 1130 -- Journal of Nutrition
Strategies to improve vitamin D status in northern European children: exploring the merits of vitamin D fortification and supplementation.
Tylavsky FA, Cheng S, Lyytikäinen A, Viljakainen H, Lamberg-Allardt C.
J Nutr. 2006 Apr;136(4):1130-4.
PMID: 16549494
Vitamin D Status and the Risk of Lung Cancer: A Cohort Study in Finland — Cancer Epidemiology, Biomarkers & Prevention
Vitamin D status and the risk of lung cancer: a cohort study in Finland.
Kilkkinen A, Knekt P, Heliövaara M, Rissanen H, Marniemi J, Hakulinen T, Aromaa A.
Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3274-8.
PMID: 18990771v
In conclusion, although there was no overall association between vitamin D and lung cancer risk, women and young participants with a higher level of vitamin D were observed to have a lower lung cancer risk. Although experimental data support the suppressing effect of vitamin D on the development of lung cancer, large epidemiologic studies from different populations with repeated measurements of vitamin D are warranted to confirm this finding. (Cancer Epidemiol Biomarkers Prev 2008;17(11):3274–8)
Serum Vitamin D and Risk of Pancreatic Cancer in the Prostate, Lung, Colorectal, and Ovarian Screening Trial -- Stolzenberg-Solomon et al. 69 (4): 1439 -- Cancer Research
Serum vitamin D and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian screening trial.
Stolzenberg-Solomon RZ, Hayes RB, Horst RL, Anderson KE, Hollis BW, Silverman DT.
Cancer Res. 2009 Feb 15;69(4):1439-47. Epub 2009 Feb 10.
PMID: 19208842
Estimates of optimal vitamin D status. - Osteoporos Int. 2005 Jul;16(7):713-6. - SpringerLink - Journal Article
Estimates of optimal vitamin D status.
Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R.
Osteoporos Int. 2005 Jul;16(7):713-6. Epub 2005 Mar 18.
PMID: 15776217
Vitamin D serum levels and allergic rhinitis. - Wiley InterScience :: Article :: HTML Full Text
Vitamin D serum levels and allergic rhinitis.
Wjst M, Hyppönen E.
Allergy. 2007 Sep;62(9):1085-6.
PMID: 17686112 DOI:
10.1111/j.1398-9995.2007.01437.x
Association between serum 25(OH)D and death from prostate cancer - British Journal of Cancer - Abstract of article
Association between serum 25(OH)D and death from prostate cancer.
Tretli S, Hernes E, Berg JP, Hestvik UE, Robsahm TE.
Br J Cancer. 2009 Feb 10;100(3):450-4. Epub 2009 Jan 20.
PMID: 19156140
doi:10.1038/sj.bjc.6604865
The serum level of 25(OH)D may be involved in disease progression and is a potential marker of prognosis in patients with prostate cancer.
Lower serum creatinine is a new risk factor of type 2 diabetes: the Kansai healthcare study. - Diabetes Care. 2009 Mar;
Lower serum creatinine is a new risk factor of type 2 diabetes: the Kansai healthcare study.
Harita N, Hayashi T, Sato KK, Nakamura Y, Yoneda T, Endo G, Kambe H.
Diabetes Care. 2009 Mar;32(3):424-6. Epub 2008 Dec 15.
PMID: 19074997
DOI: 10.2337/dc08-1265
Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects - Am J Clin Nutr. 2009 Jan 21.
Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, and ghrelin concentrations in healthy subjects.
Hlebowicz J, Hlebowicz A, Lindstedt S, Björgell O, Höglund P, Holst JJ, Darwiche G, Almér LO.
Am J Clin Nutr. 2009 Jan 21. [Epub ahead of print]
PMID: 19158209
doi:10.3945/ajcn.2008.26807
Serum ω-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers - ScienceDirect - Psychiatry Research
Conklin SM, Harris JI, Manuck SB, Yao JK, Hibbeln JR, Muldoon MF.
Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers.
Psychiatry Res. 2007 Jul 30;152(1):1-10. Epub 2007
Geographical differences in vitamin D status, with particular reference to European countries
Geographical differences in vitamin D status, with particular reference to European countries
Lars Ovesen*, Rikke Andersen and Jette Jakobsen
Institute of Food Safety and Nutrition, The Danish Veterinary and Food Administration, 30A Sydmarken, 2860 S
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