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27 Sep 09

Life expectancy - Wikipedia, the free encyclopedia

Life expectancy is the expected (in the statistical sense) number of years of life remaining at a given age.[1] It is denoted by ex, which means the average number of subsequent years of life for someone now aged x, according to a particular mortality experience. (In technical literature, this symbol means the average number of complete years of life remaining, ie excluding fractions of a year. The corresponding statistic including fractions of a year, ie the normal meaning of life expectancy, has a symbol with a small circle over the e.)

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Life Expectancy by Age, 1850–2004 — Infoplease.com

The expectation of life at a specified age is the average number of years that members of a hypothetical group of people of the same age would continue to live if they were subject throughout the remainder of their lives to the same mortality rate.

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25 Sep 09

Health Services/Technology Assessment Text (HSTAT)

The Health Services Technology/Assessment Texts (HSTAT) is a free, Web-based resource of full-text documents that provide health information and support health care decision making. HSTAT's audience includes health care providers, health service researchers, policy makers, payers, consumers and the information professionals who serve these groups.

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31 Aug 09

Dietary Reference Intakes for Vitamin D and Calcium - Institute of Medicine

Dietary Reference Intakes for Vitamin D and Calcium

An IOM committee has been named to undertake a study to assess current relevant data and update as appropriate the DRIs for vitamin D and calcium. The review will include consideration of chronic and non-chronic disease indicators. The study will also incorporate, as appropriate, systematic evidence-based reviews of the literature and an assessment of potential indicators of adequacy and of excess intake. Indicators for adequacy and excess will be selected based on the strength and quality of the evidence and the demonstrated public health significance, taking into consideration sources of uncertainty in the evidence.

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Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride : Dietary Guidance : Food and Nutrition Information Center

This DRI report presents calcium, phosphorus, magnesium, vitamin D, and fluoride, all of which have key roles in developing and maintaining bone and other calcified tissues in the body. View or download the entire 454 page document or just selected sections below, or find information for obtaining the book version.
Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride (1997)
National Academy of Sciences. Institute of Medicine. Food and Nutrition Board.

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CIA - The World Factbook -- Country Comparison :: Life expectancy at birth

This entry contains the average number of years to be lived by a group of people born in the same year, if mortality at each age remains constant in the future. The entry includes total population as well as the male and female components. Life expectancy at birth is also a measure of overall quality of life in a country and summarizes the mortality at all ages. It can also be thought of as indicating the potential return on investment in human capital and is necessary for the calculation of various actuarial measures.

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27 Aug 09

Google Book Search

Google Books for mobile is now available for Android and iPhone users.

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26 Aug 09

Vitamin D (Cholecalciferol, Calcitriol)

Bioactive vitamin D or calcitriol is a steroid hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. More recently, it has become clear that receptors for vitamin D are present in a wide variety of cells, and that this hormone has biologic effects which extend far beyond control of mineral metabolism.

The active form of vitamin D binds to intracellular receptors that then function as transcription factors to modulate gene expression. Like the receptors for other steroid hormones and thyroid hormones, the vitamin D receptor has hormone-binding and DNA-binding domains. The vitamin D receptor forms a complex with another intracellular receptor, the retinoid-X receptor, and that heterodimer is what binds to DNA. In most cases studied, the effect is to activate transcription, but situations are also known in which vitamin D suppresses transcription.

Each of the forms of vitamin D is hydrophobic, and is transported in blood bound to carrier proteins. The major carrier is called, appropriately, vitamin D-binding protein. The halflife of 25-hydroxycholecalciferol is several weeks, while that of 1,25-dihydroxycholecalciferol is only a few hours.

The vitamin D receptor binds several forms of cholecalciferol. Its affinity for 1,25-dihydroxycholecalciferol is roughly 1000 times that for 25-hydroxycholecalciferol, which explains their relative biological potencies

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info reference nutrition cholecalciferol calcidiol calcitriol metabolism synthesis edu university vitamin_D VDR VDBP DBP 25ohd binding protein receptor

Vitamin D binding protein

Also known as group specific protein (Gc), vitamin D binding protein (VDBP) is a 52Kda protein that binds monomeric actin in addition to vitamin D. The protein is 458 residues in length (Cooke, 1986), and forms three domains, the first of which contains the sterol binding site

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OMIM - VITAMIN D RECEPTOR; VDR

The vitamin D3 receptor (VDR) is an intracellular hormone receptor that specifically binds the active form of vitamin D (1,25-dihydroxyvitamin D3 or calcitriol) and interacts with target-cell nuclei to produce a variety of biologic effects

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Calcitriol receptor - Wikipedia, the free encyclopedia

The calcitriol receptor, also known as the vitamin D receptor (VDR) and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors.[1] Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or transrepression of specific geneproducts. In humans, the vitamin D receptor is encoded by the VDR gene.[2]

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25 Aug 09

Jack Handey - Wikipedia, the free encyclopedia

Jack Handey (born 25 February 1949) is an American humorist. He is best known for his Deep Thoughts, a large body of surrealistic one-liner jokes, as well as his "Fuzzy Memories" and "My Big Thick Novel" shorts. Although many people assume otherwise,[1][2] Handey is a real person, not a pen name or a character.

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20 Aug 09

Pattern recognition - Wikipedia, the free encyclopedia

Pattern recognition is "the act of taking in raw data and taking an action based on the category of the data".[citation needed] Most research in pattern recognition is about methods for supervised learning and unsupervised learning.

Pattern recognition aims to classify data (patterns) based either on a priori knowledge or on statistical information extracted from the patterns. The patterns to be classified are usually groups of measurements or observations, defining points in an appropriate multidimensional space. This is in contrast to pattern matching, where the pattern is rigidly specified.

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Pattern matching - Wikipedia, the free encyclopedia

In computer science, pattern matching is the act of checking for the presence of the constituents of a given pattern. In contrast to pattern recognition, the pattern is rigidly specified. Such a pattern concerns conventionally either sequences or tree structures. Pattern matching is used to test whether things have a desired structure, to find relevant structure, to retrieve the aligning parts, and to substitute the matching part with something else.

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19 Aug 09

Abiogenesis - Wikipedia, the free encyclopedia

In the natural sciences, abiogenesis, or "chemical evolution", is the study of how life on Earth could have arisen from inanimate matter. It should not be confused with evolution, which is the study of how groups of living things change over time. Amino acids, often called "the building blocks of life", can form via natural chemical reactions unrelated to life, as demonstrated in the Miller-Urey experiment, which involved simulating the conditions of the early Earth. In all living things, these amino acids are organized into proteins, and the construction of these proteins is mediated by nucleic acids. Thus the question of how life on Earth originated is a question of how the first nucleic acids arose.

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