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Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
Zeng XH, Zeng XJ, Li YY.
Am J Cardiol. 2003 Jul 15;92(2):173-6.
PMID: 12860219
doi:10.1016/S0002-9149(03)00533-2
Thus, berberine improved quality of life and decreased VPCs and mortality in patients with CHF.
Body mass and waist size can predict heart disease | Reuters
"A large 10-year study found that half of all fatal heart disease cases and a quarter of all non-fatal cases are linked to being overweight and having a high body mass index (BMI) or large waist.
Body mass index and waist circumference are well known risk factors for cardiovascular diseases but the Dutch researchers said their work showed BMI and waist size could actually help predict the risk of dying from or developing heart disease."
Vitamin D May Be Tied to Heart Disease Via Genes - Heart Disease and Other Cardiovascular Conditions on MedicineNet.com
"THURSDAY, Dec. 3 (HealthDay News) -- New research points to the possibility of a genetic link between vitamin D and heart disease.
People with high blood pressure who had a gene variant that reduces vitamin D activation in the body were found to be twice as likely as those without the variant to have congestive heart failure, the study found.
The finding may lead to a way to identify people at increased risk for heart disease, according to Robert U. Simpson, an assistant professor of pharmacology at the University of Michigan Medical School and his research colleagues.
They analyzed the genetic profiles of 617 people. One-third had hypertension, one-third had hypertension and congestive heart failure, and the remaining third served as healthy controls.
The researchers found that a variant in the CYP27B1 gene was associated with congestive heart failure in people with hypertension. The study is in the November issue of Pharmacogenomics."
Low Vitamin D Levels May Raise Heart Risk
"Study Shows Vitamin D Supplements May Be Useful in Preventing Heart Disease
Nov. 16, 2009 (Orlando, Fla.) -- Some men with low levels of vitamin D in their blood are at particularly high risk of developing heart disease and weakened bones that can lead to osteoporosis, researchers report.
In a study of more than 1,000 men, those with low levels of both vitamin D and the sex hormone estrogen were at significantly increased risk of having cardiovascular disease, says study head Erin Michos, MD, a cardiologist at Johns Hopkins.
"They were also at dramatically increased risk of osteopenia," or bone loss that can lead to osteoporosis, she says.
"Our results suggest that vitamin D supplements, which are already prescribed to treat osteoporosis, may also be useful in preventing heart disease," Michos tells WebMD.
Men with low levels of vitamin D and testosterone, on the other hand, were not at heightened risk for heart disease or osteopenia."
Omega 3 fatty acids from fish oil, HF treatment, and prevention
"In one room on the last day of the conference, four invited faculty members meticulously made the case for an already-available substance as an example of the kind of agent the others were looking for. Their message: omega-3 polyunsaturated fatty acids (PUFAs), usually derived from fish oil, garner far less attention as a heart-failure therapy than they deserve, given the wealth of laboratory and clinical evidence supporting a treatment effect."
NEJM -- Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups
Coronary calcium as a predictor of coronary events in four racial or ethnic groups.
Detrano R, Guerci AD, Carr JJ, Bild DE, Burke G, Folsom AR, Liu K, Shea S, Szklo M, Bluemke DA, O'Leary DH, Tracy R, Watson K, Wong ND, Kronmal RA.
N Engl J Med. 2008 Mar 27;358(13):1336-45.
PMID: 18367736
Calcium scans may be effective screening tool for heart disease | Science Blog
"LOS ANGELES (September 29, 2009) -- A simple, non-invasive test appears to be an effective screening tool for identifying patients with silent heart disease who are at risk for a heart attack or sudden death. Coronary artery calcium scans can be done without triggering excessive additional testing and costs, according to the multi-center EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) study, led by investigators at the Cedars-Sinai Heart Institute. The findings appear in today's issue of the findings appear in today's issue of the Journal of the American College of Cardiology."
Is high cholesterol good for some heart patients? | Health | Reuters
"NEW YORK (Reuters Health) - Here's an apparent paradox: High levels of artery-clogging cholesterol are a risk factor for heart disease. But such high levels have been linked to improved outcomes after a heart attack and other acute heart "events."
Now, new research suggests that this paradoxical finding may simply stem from not taking other factors into account."
Whole Health Source: Ischemic Heart Attacks: Disease of Civilization
The scientific literature contains examples of cultures that don't suffer from the chronic non-communicable diseases that are so common in modern societies. Much of what I've read indicates that heart attacks are practically unique to cultures that have adopted industrial foodways and a modern lifestyle, being infrequent or entirely absent in those that have not.
I recently came across an incredible paper from 1964 in the American Journal of Cardiology, titled "Geographic Pathology of Myocardial Infarction", by lead author Dr. Kyu Taik Lee (Am. J. Cardiol. 13:30. 1964). This was published during a period of intense research into the cardiovascular health of non-industrial cultures, including Dr. George V. Mann's famous study of the Masai.
On the Trail of the Elusive X-Factor: Vitamin K2 Revealed
Vitamin K2 is produced by animal tissues, including the mammary glands, from vitamin K1, which occurs in rapidly growing green plants.
A growing body of published research confirms Dr. Price's discoveries, namely that vitamin K2 is important for the utilization of minerals, protects against tooth decay, supports growth and development, is involved in normal reproduction, protects against calcification of the arteries leading to heart disease, and is a major component of the brain.
Vitamin K2 works synergistically with the two other "fat-soluble activators" that Price studied, vitamins A and D. Vitamins A and D signal to the cells to produce certain proteins and vitamin K then activates these proteins.
Vitamin K2 plays a crucial role in the development of the facial bones, and its presence in the diets of nonindustrialized peoples explains the wide facial structure and freedom from dental deformities that Weston Price observe
Seniors With Insufficient Levels Of Vitamin D At Increased Risk Of Dying From Heart Disease
A new study by researchers at the University of Colorado Denver and Massachusetts General Hospital (MGH) shows vitamin D plays a vital role in reducing the risk of death associated with older age. The research, just published in the Journal of the American Geriatrics Society, evaluated the association between vitamin D levels in the blood and the death rates of those 65 and older. The study found that older adults with insufficient levels of vitamin D die from heart disease at greater rates that those with adequate levels of the vitamin.
The Heart Scan Blog: Beating the Heart Association diet is child's play
In response to the Heart Scan Blog post, Post-Traumatic Grain Disorder, Anne commented:
While on the American Heart Association diet my lipids peaked in 2003. I even tried the Ornish diet for a short time, but found it impossible.
Total Cholesterol: 201
Triglycerides: 263
HDL: 62
LDL: 86
After I stopped eating gluten (I am very sensitive), my lipid panel improved slightly. This past year I started eating to keep my blood sugar under control by eliminating sugars and other grains. Now this is my most recent lab:
Total Cholesterol: 162
Triglycerides: 80
HDL: 71
LDL: 75
Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography -- Pilz et al., 10.1210/jc.2008-0784 -- Journal of Clinical Endocrinology & Metabolism
Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography.
Pilz S, März W, Wellnitz B, Seelhorst U, Fahrleitner-Pammer A, Dimai HP, Boehm BO, Dobnig H.
J Clin Endocrinol Metab. 2008 Oct;93(10):3927-35. Epub 2008 Aug 5.
PMID: 18682515
doi:10.1210/jc.2008-0784
Conclusions: Low levels of 25(OH)D and 1,25(OH)2D are associated with prevalent myocardial dysfunction, deaths due to heart failure and SCD. Interventional trials are warranted to elucidate whether vitamin D supplementation is useful for treatment and/or prevention of myocardial diseases.
Broccoli extract’s heart health benefits pinpointed?
A compound found in vegetables like broccoli, cabbage and cauliflower, may protect arteries from disease by boosting a natural defence mechanism, says a new study from the UK.
Researchers from Imperial College London (ICL) report that sulforaphane, a compound most widely associated with broccoli, may activate a protein called Nrf2 in arteries, according to findings published in Arteriosclerosis Thrombosis and Vascular Biology. While the protein is normally protective, in areas of arteries that are susceptible to disease the London-based researchers found that Nrf2 is inactive.
YouTube - Vitamin D Good For The Heart?
Vitamin D Good For The Heart? CBS NEws about Harvard Study
YouTube - Vitamin D and Cardiovascular Disease Prevention
Vitamin D and Cardiovascular Disease Prevention by Dr. David C. Sane
Welcome to to VITamin D and omegA-3 triaL (VITAL) Web site
What is VITAL?
The VITamin D and OmegA-3 TriaL (VITAL) is a research study in 20,000 U.S. men and women investigating whether taking daily dietary supplements of vitamin D (about 2000 IU) or fish oil (about 1 gram of omega-3 fatty acids) reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses. Recruitment for the study will begin in January 2010.
The Heart Scan Blog: vitamin D
Vitamin D related articles in "The Heart Scan Blog" by Dr. William Davis
Lipoprotein(a) Linked to Heart Attacks
June 9, 2009 -- Genetic testing confirms that high levels of a type of cholesterol known as lipoprotein(a) are associated with an increased risk for heart attacks, but the clinical implications of the finding are unclear.
Lipoprotein(a) has long been suspected of contributing to cardiovascular risk. But this new research offers the strongest evidence yet identifying it as an independent risk factor for heart attack.
The study appears in the June 10 issue of the Journal of the American Medical Association.
CLA-rich cheese may boost heart health: Study
Consuming cheese from ewe’s milk, rich in conjugated linoleic acid (CLA), may reduce markers linked to heart disease, suggest results from a small Italian study.
Researchers from the University of Florence report that ewe’s milk rich in cis-9, trans-11 CLA produced favourable changes in inflammatory cytokines and platelet aggregation, both of which are associated with atherosclerosis, or hardening of the arteries due to the build-up of fatty deposits on artery walls.
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