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Vitamin D replacement in Asians with diabetes may increase insulin resistance.
Vitamin D replacement in Asians with diabetes may increase insulin resistance.
Taylor AV, Wise PH.
Postgrad Med J. 1998 Jun;74(872):365-6.
PMID: 9799895
We report three cases of vitamin D replacement in British Asians with vitamin D deficiency and non-insulin-dependent diabetes mellitus. In all cases, replacement resulted in an increase in insulin resistance and a deterioration of glycaemic control
Low-Carb and Mediterranean Diets Beat Low-Fat for Weight Loss, Lipid Changes at 2 Years - Medscape
July 16, 2008 — Both a low-carbohydrate diet or a Mediterranean-style diet may be "effective alternatives" to a low-fat diet, with more favorable effects on lipids and/or glycemic control, new research suggests [1]. The two-year study, which managed to keep almost 85% of the 322 study participants on one of the three diets for the entire period, offers the hope that weight-loss diets can be tailored to personal preferences, without sacrificing efficacy, researchers say.
"Several recent one-year dietary studies have led the American Diabetes Association to state in January 2008 that low-carb diets should be considered for a maximum of one year," lead author on the study, Dr Iris Shai (Ben Gurion University of the Negev, Beer-Sheva, Israel), told heartwire . "The current two-year study suggests that one low-fat diet doesn't fit all, meaning that the old paradigm should be reconsidered."
Shai and colleagues publish the results of the Dietary Intervention Randomized Controlled Trial (DIRECT) in the July 17, 2008 issue of the New England Journal of Medicine
Low-carb and Mediterranean diets beat low-fat for weight-loss, lipid changes at two years - theheart.org
July 16, 2008 | Shelley Wood
Beer-Sheva, Israel - Both a low-carbohydrate diet or a Mediterranean-style diet may be "effective alternatives" to a low-fat diet, with more favorable effects on lipids and/or glycemic control, new research suggests [1]. The two-year study, which managed to keep almost 85% of the 322 study participants on one of the three diets for the entire period, offers the hope that weight-loss diets can be tailored to personal preferences, without sacrificing efficacy, researchers say.
"Several recent one-year dietary studies have led the American Diabetes Association to state in January 2008 that low-carb diets should be considered for a maximum of one year," lead author on the study, Dr Iris Shai (Ben Gurion University of the Negev, Beer-Sheva, Israel), told heartwire. "The current two-year study suggests that one low-fat diet doesn't fit all, meaning that the old paradigm should be reconsidered."
Shai and colleagues publish the results of the Dietary Intervention Randomized Controlled Trial (DIRECT) in the July 17, 2008 issue of the New England Journal of Medicine
NEJM -- Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet
Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.
Shai I, Schwarzfuchs D, Henkin Y, Shahar DR, Witkow S, Greenberg I, Golan R, Fraser D, Bolotin A, Vardi H, Tangi-Rozental O, Zuk-Ramot R, Sarusi B, Brickner D, Schwartz Z, Sheiner E, Marko R, Katorza E, Thiery J, Fiedler GM, Blüher M, Stumvoll M, Stampfer MJ; Dietary Intervention Randomized Controlled Trial (DIRECT) Group.
N Engl J Med. 2008 Jul 17;359(3):229-41.
PMID: 18635428
Conclusions Mediterranean and low-carbohydrate diets may be effective alternatives to low-fat diets. The more favorable effects on lipids (with the low-carbohydrate diet) and on glycemic control (with the Mediterranean diet) suggest that personal preferences and metabolic considerations might inform individualized tailoring of dietary interventions. (ClinicalTrials.gov number, NCT00160108 [ClinicalTrials.gov] .)
Vitamin D and diabetes: Improvement of glycemic control with vitamin D3 repletion -- Schwalfenberg 54 (6): 864 -- Canadian Family Physician
Vitamin D and diabetes: improvement of glycemic control with vitamin D3 repletion.
Schwalfenberg G.
Can Fam Physician. 2008 Jun;54(6):864-6.
PMID: 18556494
Conclusion
These cases support information that is already known about VTD and its effect on the islet cell. As discussed above, this might be true only for vitamin D3 and not vitamin D2, although vitamin D2 has been shown to improve bone health. Vitamin D insufficiency or deficiency is common, and repletion might improve glycemic control early in type 2 diabetes. Diabetes is one of the fastest growing chronic diseases worldwide. Vitamin D3 is inexpensive and readily available. Well-designed clinical studies are required to ascertain if improving 25(OH)D levels from an insufficiency or deficiency to sufficiency improves glycemic control in diabetes. These studies need to be properly designed: a randomized controlled trial with VTD deficiency or insufficiency identified in diabetic patients of various ethnic
Baseline Serum 25-Hydroxy Vitamin D Is Predictive of Future Glycemic Status and Insulin Resistance - Diabetes
Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000.
Forouhi NG, Luan J, Cooper A, Boucher BJ, Wareham NJ.
Diabetes. 2008 Oct;57(10):2619-25. Epub 2008 Jun 30.
PMID: 18591391
doi: 10.2337/db08-0593
CONCLUSIONS: This prospective study reports inverse associations between baseline serum 25(OH)D and future glycemia and insulin resistance. These associations are potentially important in understanding the etiology of abnormal glucose metabolism and warrant investigation in larger, specifically designed prospective studies and randomized controlled trials of supplementation.
Supplementation with cholecalciferol does not improve glycaemic control in diabetic subjects with normal serum 25-hydroxyvitamin D levels. - SpringerLink - Journal Article
Supplementation with cholecalciferol does not improve glycaemic control in diabetic subjects with normal serum 25-hydroxyvitamin D levels.
Jorde R, Figenschau Y.
Eur J Nutr. 2009 Apr 16. [Epub ahead of print]
PMID: 19370371
10.1007/s00394-009-0020-3
Conclusions We were not able to demonstrate that vitamin D supplementation had a significant effect on glucose metabolism in subjects with type 2 diabetes but without vitamin D deficiency. Further studies are needed in larger groups of subjects with type 2 diabetes or impaired glucose tolerance, who also exhibit low serum 25-hydroxyvitamin D levels.
Response -- Schwalfenberg 53 (9): 1435 -- Canadian Family Physician
Vitamin D supplementation.
Eveleigh B.
Can Fam Physician. 2007 Sep;53(9):1435; author reply 1435.
PMID: 17872869
My concern regarding vitamin D2 is that it is a synthetic analogue and might interact with the vitamin D receptor differently in various cell systems. It has been reported that vitamin D3 might improve glycemic control.7 Vitamin D2 has been reported to cause worsening of glycemic control in people of East Indian descent.8 Is this because of vitamin D receptor polymorphism, or because of enhanced 24-hydroxylase enzyme activation, or is it due to how vitamin D2 interacts with the receptor? Until this has been sorted out, I feel safest using vitamin D3. There are about 2000 synthetic analogues of vitamin D. The search is on for one that can cross the blood-brain barrier to treat certain types of brain cancers without causing hypercalcemia.9 But then again, what other effects would this compound have? There are still so many unknowns
20 Body Language Tricks That Let You Control Conversations
Your body language says a lot about you and your reaction to a conversation you are having.You can lose control of a conversation easily with poor body language. Depending on the type of conversation you are engaged in, here are some tips to give you more control over a conversation.\n
Don't cure cancer, stabilize it: Scientific American Blog
What if we didn’t try to cure cancer, but simply kept tumors from growing too big? That’s what radiologist Robert Gatenby of the Moffitt Cancer Center proposes this week in the journal Nature.
Gatenby argues that high doses of powerful chemotherapies wreak havoc on a patient’s immune system and foster the rapid regrowth of chemoresistant cancers that doctors have no hope of fighting. So instead of curing cancer, he suggests doctors aim to stabilize the tumor at a tolerable size.
In practice, this would mean that doctors identify a target size for an individual tumor that gives the patient the best quality of life. Then, they will regularly monitor the tumor’s growth with medical imaging equipment like a PET/CT scanner (see photo), and regulate doses of anticancer drugs to maintain it at a precise volume.
Unfuddle: Free Source Control, Bug and Issue Tracking
Unfuddle is a secure, hosted software development environment and project management solution for small software development teams
Twitter Support
With Twitter control from both phone and web, Twitter is at your beck and call! Choose whose text messages you do and don't want to receive on your phone, and invite your friends. Turn Twitter off when you need a break and on again when you can't resist
Cidero - UPnP Control Point and UPnP Bridge Software
Welcome to Cidero! Here you will find a variety of software applications and utilities, focused on UPnP-based media distribution and control in the networked home environment. All applications are freely available, and full source code is included for the
PLoS ONE: Losing the Big Picture: How Religion May Control Visual Attention
Colzato LS, van den Wildenberg WPM, Hommel B (2008)
Losing the Big Picture: How Religion May Control Visual Attention.
PLoS ONE 3(11): e3679.
doi:10.1371/journal.pone.0003679
In sum, given that real-life objects and events are commonly complex and hierarchically structured, so that their perceptual organization and semantic interpretation often hinges on the aspect or level an observer attends to, it seems possible that religious beliefs may indeed lead to different and sometimes discrepant and incompatible interpretations of the same incident. That this can happen is a well-known empirical fact but that it can originate in basic automatic visual operations that precede conscious representation is surprising and in some sense worrying—as it seems to work against the scientific ideal that careful observation is sufficient to reach agreements about basic facts and what we consider reality. Our findings are consistent with the New Look on perception [1] in confirming that perceptual processes can be affected by the cognitive states of the observer. To some degree they challenge, however, previous claims that culture has an important impact on perception. Even though our findings do not rule out this possibility, they show that religion makes a difference even if culture is controlled for. Given that previous reports on culture-related differences did not control for religion [2], [3], it is possible that religious differences are sufficient to account for the available evidence.
On the Origin of Specious Arguments » American Scientist
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The central dogma of this book, repeated by many separate contributors, is that natural selection processes smile on “redundancy, flexibility, and diffuse control” and that “an organization of semiautonomous parts under weak central authority” is most likely to survive in a variety of threat environments, because different organisms can experiment with different reactive strategies to see which works best.
ATI Catalyst™ Software Suite Version 7.6
ATI Catalyst™ Software Suite Version 7.6
This release note provides information on the latest posting of AMD's industry leading software suite, Catalyst™. This particular software suite updates both the AMD Display Driver, and the Catalyst™ Contr
Royal Philips Electronics - RC9800i
Smart remote control for with screen for videos, stereos and upnp media players.
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