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Clinical Prevention of Sudden Cardiac Death by n-3 Polyunsaturated Fatty Acids and Mechanism of Prevention of Arrhythmias by n-3 Fish Oils -- Leaf et al. 107 (21): 2646 -- Circulation
Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils.
Leaf A, Kang JX, Xiao YF, Billman GE.
Circulation. 2003 Jun 3;107(21):2646-52. Review.
PMID: 12782616
doi: 10.1161/01.CIR.0000069566.78305.33
This review will be limited specifically to the beneficial prevention by the n-3 polyunsaturated fatty acids (PUFAs) of arrhythmic deaths, including sudden cardiac death, which annually causes some 300 000 deaths in the United States and millions more worldwide. We will also show that the growing body of positive clinical studies is supported by what has been learned in animal and laboratory studies regarding the mechanism by which n-3 PUFAs prevent cardiac arrhythmias.
Use of vitamin D in clinical practice. - Altern Med Rev. 2008 Mar
Use of vitamin D in clinical practice.
Cannell JJ, Hollis BW.
Altern Med Rev. 2008 Mar;13(1):6-20.
PMID: 18377099
The recent discovery--from a meta-analysis of 18 randomized controlled trials--that supplemental cholecalciferol (vitamin D) significantly reduces all-cause mortality emphasizes the medical, ethical, and legal implications of promptly diagnosing and adequately treating vitamin D deficiency. Not only are such deficiencies common, and probably the rule, vitamin D deficiency is implicated in most of the diseases of civilization. Vitamin D's final metabolic product is a potent, pleiotropic, repair and maintenance, seco-steroid hormone that targets more than 200 human genes in a wide variety of tissues, meaning it has as many mechanisms of action as genes it targets. One of the most important genes vitamin D up-regulates is for cathelicidin, a naturally occurring broad-spectrum antibiotic. Natural vitamin D levels, those found in humans living in a sun-rich environment, are between 40-70 ng per ml, levels obtained by few modern humans. Assessing serum 25-hydroxy-vitamin D (25(OH)D) is the only way to make the diagnosis and to assure treatment is adequate and safe. Three treatment modalities exist for vitamin D deficiency: sunlight, artificial ultraviolet B (UVB) radiation, and vitamin D3 supplementation. Treatment of vitamin D deficiency in otherwise healthy patients with 2,000-7,000 IU vitamin D per day should be sufficient to maintain year-round 25(OH)D levels between 40-70 ng per mL. In those with serious illnesses associated with vitamin D deficiency, such as cancer, heart disease, multiple sclerosis, diabetes, autism, and a host of other illnesses, doses should be sufficient to maintain year-round 25(OH)D levels between 55 -70 ng per mL. Vitamin D-deficient patients with serious illness should not only be supplemented more aggressively than the well, they should have more frequent monitoring of serum 25(OH)D and serum calcium. Vitamin D should always be adjuvant treatment in patients with serious ill
Measuring 25-hydroxyvitamin D in a clinical environment: challenges and needs -- Hollis 88 (2): 507S -- American Journal of Clinical Nutrition
Measuring 25-hydroxyvitamin D in a clinical environment: challenges and needs.
Hollis BW.
Am J Clin Nutr. 2008 Aug;88(2):507S-510S. Review.
PMID: 18689391
In this article, I provide an overview of the techniques available for measuring 25(OH)D, compare these techniques with one another, and assess their clinical utility. I also briefly discuss the stability of 25(OH)D in biological media and present an overview of the Vitamin D External Quality Assessment Scheme.
Factors Associated With Clinical Benefit From Epidermal Growth Factor Receptor Inhibitors in Recurrent and Metastatic Squamous Cell Carcinoma of the Head and Neck - OncologySTAT
Factors associated with clinical benefit from epidermal growth factor receptor inhibitors in recurrent and metastatic squamous cell carcinoma of the head and neck.
Cohen EE, Halpern AB, Kasza K, Kocherginsky M, Williams R, Vokes EE.
Oral Oncol. 2009 Oct;45(10):e155-60. Epub 2009 Jul 7.
PMID: 19586795
The clinical importance of vitamin D (cholecalciferol): a paradigm shift with implications for all healthcare providers. - Altern Ther Health Med. 2004 Sep-Oct;10(5):28-36; quiz 37, 94. (full etxt PDF)
The clinical importance of vitamin D (cholecalciferol): a paradigm shift with implications for all healthcare providers.
Vasquez A, Manso G, Cannell J.
Altern Ther Health Med. 2004 Sep-Oct;10(5):28-36; quiz 37, 94. Review.
PMID: 15478784
Clinical Guide to Sunscreens and Photoprotection - Google Books
Designed with practicing dermatologists, dermatology trainees, physicians, and scientists interested in photoprotection in mind, this concise and highly illustrated guide provides the latest knowledge of photoprotection in dermatology and cosmetic science. Clinical Guide to Sunscreens and Photoprotectionalso addresses recent important international and domestic regulatory activity and requirements on the use of novel sun protective chemicals and proper labeling of products to ensure increased consumer awareness.This concisely written, problem-oriented text explores
See chapter by Bischoff-Ferrari et al. from page 119 dealing with what dose is needed for 25(OH)D level of 80 nmol/l in 97% of population
Vitamin D Status: Measurement, Interpretation, and Clinical Application
Vitamin D status: measurement, interpretation, and clinical application.
Holick MF.
Ann Epidemiol. 2009 Feb;19(2):73-8. Epub 2008 Mar 10. Review.
PMID: 18329892
Conclusion
The only way to determine whether a person is vitamin D deficient or sufficient is to measure their circulating level of 25(OH)D. There are a variety of assays used to measure 25(OH)D. The radioimmunoassays and competitive protein binding assays for 25(OH)D are useful in detecting vitamin D deficiency and sufficiency. However, these assays are fraught with technical difficulties, especially if they are not run routinely (Fig. 4) (33). Several reference laboratories have now switched to LC-MS ,which measures both 25(OH)D2 and 25(OH)D3 quantitatively. The total 25(OH)D, i.e., 25(OH)D2 plus 25(OH)D3, is what physicians need to be aware of for their patients. A level >30 ng/mL is
Nutrition: Arbor Nutrition Guide
Welcome to the Arbor Nutrition Guide.\nEditor-in-chief: Dr.Tony Helman\nLast files updated 20 November 2005\n\nThis site has thousands of links, and not all of them are current.\nWe are engaged in a cycle of checking and updating them, section by section. \n\nYou can also enrol for the free Arbor Clinical Nutrition Updates, a regular, independent, concise report on the latest important research findings in nutrition.
PubMed Central | Open Access to Medical Articles
Receive notice of new journals and other major updates to PMC: join the PMC News mail list or subscribe to the PMC News RSS feed .\nAll the articles in PMC are free (sometimes on a delayed basis). Some journals go beyond free, to Open Access. Find out what that means.\nPMC's utilities include an OAI service that provides XML of the full-text of some articles, functions for scripting PMC searches and linking to specific PMC articles from your site, and more .
Probiotic yogurt in the elderly with intestinal bacterial overgrowth: endotoxaemia and innate immune functions. - .[Br J Nutr. 2009] - PubMed Result
Probiotic yogurt in the elderly with intestinal bacterial overgrowth: endotoxaemia and innate immune functions.
Schiffrin EJ, Parlesak A, Bode C, Bode JC, van't Hof MA, Grathwohl D, Guigoz Y.
Br J Nutr. 2009 Apr;101(7):961-6.
PMID: 19353762
Clinical Trial Results Show Proof-of-Concept For Use Of Coriolus Versicolor As Immunonutrition In HPV Patients With Cervical Lesions (LSIL)
The results of a year long clinical trial examining the effects of mushroom supplementation in patients with Human Papillomavirus (HPV) have recently been presented at congress. Dr. Jose Silva Couto and Dr. Daniel Pereira da Silva of the Cervical Pathology Unit of the Portuguese Institute of Oncology in Coimbra, Portugal presented their findings at the 20th European Congress of Obstetrics and Gynaecology, in Lisbon Portugal. This study provides a promising set of results and demonstrates proof-of concept for the question as to whether immunonutrition supplements can be successfully used to improve HPV status in patients.
Coriolus versicolor and cancer (June 2003)
Attached please find the final draft of Dr. Kenyon's non-controlled observational study on the use of Coriolus versicolor (non-extracted) in 30 solid tumour cancer patients. The final report will be published in the February edition of Mycology News 7.
The patients were Stage III and Stage IV patients in which chemotherapy and radiotherapy were not considered successful. Below please find a synopsis of patient type.
Anergy testing in patients with head and neck cancer. - [Asian Pac J Allergy Immunol. 2003] - PubMed Result
Anergy testing in patients with head and neck cancer.
Pumhirun P, Wasuwat P.
Asian Pac J Allergy Immunol. 2003 Sep;21(3):189-92. Erratum in: Asian Pac J Allergy Immunol. 2003 Dec;21(4):277.
PMID: 15032403
Vitamin D, a Gene-Regulating Super-Nutrient
Your cells use vitamin D to directly regulate your genes, making it one of the most powerful compounds in human health.
Head and Neck Cancer Summary from 2006 ASCO Annual Meeting
American Society of Clinical Oncology Meeting 2006.
American Society of Clinical Oncology - ASCO
The American Society of Clinical Oncology (ASCO) is a non-profit organization, founded in 1964, with overarching goals of improving cancer care and prevention and ensuring that all patients with cancer receive care of the highest quality. More than 25,000 oncology practitioners belong to ASCO, representing all oncology disciplines (medical, radiation, and surgical oncology) and subspecialties. Members include physicians and health-care professionals participating in approved oncology training programs, oncology nurses, and other practitioners with a predominant interest in oncology.
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