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Eggs distinctly modulate plasma carotenoid and lipoprotein subclasses in adult men following a carbohydrate-restricted diet.
Mutungi G, Waters D, Ratliff J, Puglisi M, Clark RM, Volek JS, Fernandez ML.
J Nutr Biochem. 2009 Apr 13. [Epub ahead of print]
PMID: 19369056

We previously reported that carbohydrate restriction (CR) (10-15% en) during a weight loss intervention lowered plasma triglycerides (TG) by 45% in male subjects (P<.001). However, those subjects with a higher intake of cholesterol provided by eggs (640 mg additional cholesterol, EGG group) had higher concentrations of high-density lipoprotein (HDL) cholesterol (P<.0001) than the individuals consuming lower amounts (0 mg of additional cholesterol, SUB group). The objectives of the present study were to evaluate whether CR and egg intake (1) modulate circulating carotenoids and (2) affect the concentrations of plasma apolipoproteins (apo), lipoprotein size and subfraction distribution. CR decreased the number of large and medium very low-density lipoprotein cholesterol subclasses (P<.001), while small low-density lipoprotein (LDL) were reduced (P<.001). In agreement with these observations, a decrease in apo B (P<.01) was observed. In addition, CR resulted in a 133% increase in apo C-II and a 65% decrease in apo C-III (P<.0001). Although an increase of the larger LDL subclass was observed for all subjects, the EGG group had a greater increase (P<.05). The EGG group also presented a higher number of large HDL particles (P<.01) compared to the SUB group. Regarding carotenoids, CR resulted in no changes in dietary or plasma alpha- or beta-carotene and beta-cryptoxanthin, while there was a significant reduction in both dietary and plasma lycopene (P<.001). In contrast, dietary lutein and zeaxanthin were increased during the intervention (P<.05). However, only those subjects from the EGG group presented higher concentrations of these two carotenoids in plasma, which were correlated with the higher concentrations of large LDL observed in the EGG group. Th

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2009 April study research clinical_trial humans adults men egg eggs consumption modulate plasma carotenoid lipoprotein subclasses carbohydrate-restricted diet carbohydrate-restricted_diet nutrition low-carbohydrate low-carbohydrate_diet HDL LDL_size

Consumption of cod and weight loss in young overweight and obese adults on an energy reduced diet for 8-weeks.\nRamel A, Jonsdottir MT, Thorsdottir I.\nNutr Metab Cardiovasc Dis. 2009 Dec;19(10):690-6. Epub 2009 Apr 8.\nPMID: 19356912\n\nConclusion\nA dose-response relationship between cod consumption and weight loss during an 8-week energy restriction diet is found and 5×150g cod/week results in 1.7kg greater weight loss in young overweight or obese adults than a isocaloric diet without seafood

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2009 December nmcd-journal study research clinical_trial rct humans obesity nutrition fish cod consumption weight loss diet fish_protein cod_protein weight-loss_diet dose-response CVD overweight young obese adults weight_loss Iceland

Correlation of symptoms with vitamin D deficiency and symptom response to cholecalciferol treatment: a randomized controlled trial.
Arvold DS, Odean MJ, Dornfeld MP, Regal RR, Arvold JG, Karwoski GC, Mast DJ, Sanford PB, Sjoberg RJ.
Endocr Pract. 2009 May-Jun;15(3):203-12.
PMID: 19364687

Conclusions: Compared with participants in the placebo group, patients in the treatment group showed mild short-term improvement in the overall fibromyalgia impact score, but did not show significant improvement in most musculoskeletal symptoms or in activities of daily living.

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2009 May study research clinical_trial rct humans adults vitamin_D deficiency low_levels symptoms response cholecalciferol vitamin_D3 supplementation treatment fibromyalgia nutrition medline

Depression is associated with decreased 25-hydroxyvitamin D and increased parathyroid hormone levels in older adults.
Hoogendijk WJ, Lips P, Dik MG, Deeg DJ, Beekman AT, Penninx BW.
Arch Gen Psychiatry. 2008 May;65(5):508-12.
PMID: 18458202

Conclusion The results of this large population-based study show an association of depression status and severity with decreased serum 25(OH)D levels and increased serum PTH levels in older individuals.

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2008 May archpsyc study research epidemiological humans elderly old older vitamin_D depression 250hd deficiency low_levels nutrition medline severity PTH adults

Vitamin D and cognitive performance in adults: a systematic review.
Annweiler C, Allali G, Allain P, Bridenbaugh S, Schott AM, Kressig RW, Beauchet O.
Eur J Neurol. 2009 Oct;16(10):1083-9. Epub 2009 Jul 29.
PMID: 19659751
DOI: 10.1111/j.1468-1331.2009.02755.x

This systematic review shows that the association between serum 25OHD concentrations and cognitive performance is not yet clearly established. The inconclusive results of the reviewed studies could be due to methodology, types of the cognitive tasks used and/or the cellular mechanisms of vitamin D.

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2009 October study systematic review humans adults vvitamin_D nutrition cognition cognitive performance cognitive_performance aging ageing 25ohd memory medline

Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults.
Lang IA, Galloway TS, Scarlett A, Henley WE, Depledge M, Wallace RB, Melzer D.
JAMA. 2008 Sep 17;300(11):1303-10. Epub 2008 Sep 16.
PMID: 18799442

Conclusion Higher BPA exposure, reflected in higher urinary concentrations of BPA, may be associated with avoidable morbidity in the community-dwelling adult population.

jama.ama-assn.org/...1303 - Preview

2008 September JAMA study research epidemiological humans adults USA Bisphenol_A BPA urinary morbidity healt nutrition medline CVD diabetes

Vitamin d deficiency and seasonal variation in an adult South Florida population.
Levis S, Gomez A, Jimenez C, Veras L, Ma F, Lai S, Hollis B, Roos BA.
J Clin Endocrinol Metab. 2005 Mar;90(3):1557-62. Epub 2005 Jan 5.
PMID: 15634725

The prevalence of hypovitaminosis D is considerable even in southern latitudes and should be taken into account in the evaluation of postmenopausal and male osteoporosis.

jcem.endojournals.org/...1557 - Preview

2005 March jcem study research epidemiological humans adults sunny south southern Florida vitamin_D deficiency prevalence season seasonal variation nutrition Hollis 25ohd medline hypovitaminosis_D

Vitamin D deficiency and bone health in healthy adults in Finland: could this be a concern in other parts of Europe?
Lamberg-Allardt CJ, Outila TA, Kärkkainen MU, Rita HJ, Valsta LM.
J Bone Miner Res. 2001 Nov;16(11):2066-73.
PMID: 11697803

Low vitamin D status was prevalent in these young adults in northern Europe in winter, although the vitamin D intake met the recommendation. This probably is not a local problem for northern Europe, because the natural sources of vitamin D are scarce and fortification is not very common in Europe, and with the exception of the southern part of Europe, sunshine is not very abundant in this part of the world. Thus, the results of this study indicate that more attention should be focused on vitamin D status and the sources of vitamin D in these countries.

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2001 November study research epidemiological humans Finnish Finland healthy adults vitamin_D deficiency prevalence bone health concern Europe Lamberg-Allardt nutrition medline bone_health osteoporosis prevention PTH iPTH 25ohd

Development of a model for optimal food fortification: vitamin D among adults in Finland.
Hirvonen T, Sinkko H, Valsta L, Hannila ML, Pietinen P.
Eur J Nutr. 2007 Aug;46(5):264-70. Epub 2007 May 18.
PMID: 17514377

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2007 August ejn study research development model optimal food fortification vitamin_D adults Finland nutrition medline

Prevalence of vitamin D insufficiency in an adult normal population.
Chapuy MC, Preziosi P, Maamer M, Arnaud S, Galan P, Hercberg S, Meunier PJ.
Osteoporos Int. 1997;7(5):439-43.
PMID: 9425501

www.ncbi.nlm.nih.gov/...9425501 - Preview

1997 study research epidemiological humans adults France vitamin_D insufficiency deficiency 25ohd prevalence nutrition medline

The prevalence of hypovitaminosis D among US adults: data from the NHANES III.
Zadshir A, Tareen N, Pan D, Norris K, Martins D.
Ethn Dis. 2005 Autumn;15(4 Suppl 5):S5-97-101.
PMID: 16315387

CONCLUSION: Serum levels of 25(OH) D3 are below the recommended levels for a large portion of the general adult population and in most minorities. Need exists for a critical review and probable revision of current recommendations for adult vitamin D intake to maintain adequate 25(OH) D3 levels.

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2005 study research epidemiological humans vitamin_D 25ohd deficiency hypovitaminosis_D prevalence USA adults NHANES III NHANES_III nutrition medline black white hispanic ethnicity race

Vitamin D status in apparently healthy adults in Kashmir Valley of Indian subcontinent.
Zargar AH, Ahmad S, Masoodi SR, Wani AI, Bashir MI, Laway BA, Shah ZA.
Postgrad Med J. 2007 Nov;83(985):713-6.
PMID: 17989271
doi:10.1136/pgmj.2007.059113

Conclusions: In spite of abundant sunlight, healthy individuals in Kashmir valley are vitamin D deficient, particularly women. Serum 25 (OH) D concentrations are significantly related to sun exposure

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2007 November study research epidemiological humans adults vitamin_D deficiency prevalence Kashmir Valley India sun sunshine sunny country status exposure 25ohd nutrition medline

Heliotherapy improves vitamin D balance and atopic dermatitis.
Vähävihu K, Ylianttila L, Salmelin R, Lamberg-Allardt C, Viljakainen H, Tuohimaa P, Reunala T, Snellman E.
Br J Dermatol. 2008 Jun;158(6):1323-8. Epub 2008 Mar 20.
PMID: 18363748
DOI: 10.1111/j.1365-2133.2008.08518.x

CONCLUSIONS: A 2-week course of HT significantly improved vitamin D balance by increasing serum calcidiol concentration, and caused a marked healing of AD. These parallel positive responses should be taken into account when the benefits of HT are considered..

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2008 June study research clinical_trial adults sun sunlight Heliotherapy atopic dermatitis atopic_dermatitis atopy vitamin_D climate therapy UV UVB Lamberg-Allardt Viljakainen Tuohimaa 25ohd nutrition medline

A randomized controlled trial of vitamin D3 supplementation for the prevention of symptomatic upper respiratory tract infections.
Li-Ng M, Aloia JF, Pollack S, Cunha BA, Mikhail M, Yeh J, Berbari N.
Epidemiol Infect. 2009 Mar 19:1-9. [Epub ahead of print]
PMID: 19296870

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2009 March study research clinical_trial rct humans adults vitamin_D supplemenration cold common common_cold flu URI prevention nutrition medline 25ohd Aloia

BACKGROUND: To determine the effect of vitamin D binding protein (DBP) genotypes on 25-hydroxyvitamin D [25(OH)D] changes with vitamin D supplements, we studied 98 adults receiving 600 or 4000 IU/d vitamin D(3) for one year. METHODS: The DBP functional variant, T436K, was genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). RESULTS: Mean 25(OH)D increases were 97% for TT (n=48), 151% for TK (n=31) and 307% (n=6) for KK genotypes (p=.004). CONCLUSIONS: As with baseline 25(OH)D, T436K genotype predicts 25(OH)D changes after long-term vitamin D supplementation.

Common genetic variants of the vitamin D binding protein (DBP) predict differences in response of serum 25-hydroxyvitamin D [25(OH)D] to vitamin D supplementation.
Fu L, Yun F, Oczak M, Wong BY, Vieth R, Cole DE.
Clin Biochem. 2009 Jul;42(10-11):1174-7. Epub 2009 Mar 18.
PMID: 19302999

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2009 July study research clinical_trial humans adults Vieth vitamin_D binding protein vitamin_D_binding_protein DBP 25ohd dosing dosage dose-response genotype genetics supplementation nutrition T436K variant polymorphism Toronto university Canada VDBP

One of the major building blocks of the brain, the omega-3 fatty acid docosahexaenoic acid (DHA) is critical for optimal brain health and function at all ages of life. Researchers are now finding that DHA provides brain-boosting benefits in infants and aging adults.

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2008 January LEF LE magazine news report DHA brain developmen neuroprotective neurological function nutrition omega-3 infants aging adults learning memory behavior cognition

Primary vitamin D deficiency in adults.\nDrug Ther Bull. 2006 Apr;44(4):25-9. Review.\nPMID: 16617932 [PubMed - indexed for MEDLINE]

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vitamin D Primary deficiency adults insufficiency prevalence medicine medline nutrition study science peer-reviewed review imported delicious vitamin_D

Kiecolt-Glaser JK, Belury MA, Porter K, Beversdorf DQ, Lemeshow S, Glaser R.
Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults.
Psychosom Med. 2007 Apr;69(3):217-24. Epub 2007 Mar 30.
PMID: 17401057 [PubMed - indexed f

www.psychosomaticmedicine.org/...217 - Preview

Depressive Symptoms depression omega-6 omega-3 ratio balance Fatty Acids fat Inflammation Older Adults old elderly aging aged people health medicine medline nutrition study science peer-reviewed imported delicious

Goodrow EF, Wilson TA, Houde SC, Vishwanathan R, Scollin PA, Handelman G, Nicolosi RJ.
Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentra

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nutrition eggs egg serum lutein zeaxanthin older adults lipids lipoproteins cholesterol ldl hdl chd coronary cvd cardiovascular disease science scientific research study article peer-reviewed medline medicine 2006 imported delicious lipid_profile