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Vitamin D for cancer prevention: global perspective. Garland CF et al. -Ann Epidemiol. 2009 Jul;19(7):468-83 (full text PDF)
Vitamin D for cancer prevention: global perspective.
Garland CF, Gorham ED, Mohr SB, Garland FC.
Ann Epidemiol. 2009 Jul;19(7):468-83. Review.
PMID: 19523595
GrassrootsHealth | Vitamin D Action - Vitamin D Scientists' Call to Action Statement
"We are aware of substantial scientific evidence supporting the role of vitamin D in prevention of cancer. It has been reasonably established that adequate serum vitamin D metabolite levels are associated with substantially lower incidence rates of several types of cancer, including those of the breast, colon, and ovary, and other sites.
We have concluded that the vitamin D status of most individuals in North America will need to be greatly improved for substantial reduction in incidence of cancer. Epidemiological studies have shown that higher vitamin D levels are also associated with lower risk of Type I diabetes in children and of multiple sclerosis. Several studies have found that markers of higher vitamin D levels are associated with lower incidence and severity of influenza and several other infectious diseases."
(VIDEO) Shedding light on the vitamin D deficiency 'crisis' - thebahamasweekly.com
(VIDEO) Shedding light on the vitamin D deficiency ‘crisis’
By GrassRootsHealth.com
Oct 11, 2009 - 4:49:39 PM
San Diego, CA - Can vitamin D prevent 80% of the incidence of breast cancer? What is its affect on colon cancer and other major illnesses? These questions and more will be addressed when some of the most prominent vitamin D researchers in North America participate in the " Diagnosis & Treatment of Vitamin D Deficiency" seminar presented by GrassrootsHealth at the University of Toronto on Tuesday, November 3 from 8 a.m. - 5 p.m.
GrassrootsHealth is the founder of D*action, an international public health project whose goal is to solve the vitamin D deficiency epidemic. GrassrootsHealth and D*action work with over 30 scientists, institutions and individuals committed to educate, test, and study vitamin D levels worldwide.
At the conference, a group of physicians and researchers in the vitamin D field will discuss vitamin D's role in the potential prevention of many diseases, including breast cancer, colon cancer, type 1 diabetes and multiple sclerosis, the ultimate reduction in the incidence of infectious diseases and the economic impact of such action
Vitamin D, Type 1 Diabetes and Cancer - UCSD seminar - April 9, 2008
Vitamin D, Type 1 Diabetes and Cancer
April 9, 2008
Cedric F. Garland1, Frank C. Garland1,
Edward D. Gorham1, William B. Grant2
and Sharif B. Mohr1
1University of California, San Diego CA
Department of Family and Preventive Medicine
2Sunlight, Nutrition & Health Research Center (SUNARC),
San Francisco CA
The Role of Vitamin D in Cancer Prevention -- Garland et al. 96 (2): 252 -- American Journal of Public Health
The role of vitamin D in cancer prevention.
Garland CF, Garland FC, Gorham ED, Lipkin M, Newmark H, Mohr SB, Holick MF.
Am J Public Health. 2006 Feb;96(2):252-61. Epub 2005 Dec 27. Review.
PMID: 16380576
DOI: 10.2105/AJPH.2004.045260
Vitamin D status differs by latitude and race, with residents of the northeastern United States and individuals with more skin pigmentation being at increased risk of deficiency. A PubMed database search yielded 63 observational studies of vitamin D status in relation to cancer risk, including 30 of colon, 13 of breast, 26 of prostate, and 7 of ovarian cancer, and several that assessed the association of vitamin D receptor genotype with cancer risk.
The majority of studies found a protective relationship between sufficient vitamin D status and lower risk of cancer. The evidence suggests that efforts to improve vitamin D status, for example by vitamin D supplementation, could reduce cancer incidence and mortality at low cost, with few or no adverse effects.
Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. - [Lancet. 1989] - PubMed Result
Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study.
Garland CF, Comstock GW, Garland FC, Helsing KJ, Shaw EK, Gorham ED.
Lancet. 1989 Nov 18;2(8673):1176-8.
PMID: 2572900
Blood samples taken in 1974 in Washington County, Maryland, from 25 620 volunteers were used to investigate the relation of serum 25-hydroxyvitamin D (25-OHD) with subsequent risk of getting colon cancer. 34 cases of colon cancer diagnosed between August, 1975, and January, 1983, were matched to 67 controls by age, race, sex, and month blood was taken. Risk of colon cancer was reduced by 75% in the third quintile (27-32 ng/ml) and by 80% in the fourth quintile (33-41 ng/ml) of serum 25-OHD. Risk of getting colon cancer decreased three-fold in people with a serum 25-OHD concentration of 20 ng/ml or more. The results are consistent with a protective effect of serum 25-OHD on colon cancer.
The Association of Solar Ultraviolet B (UVB) with Reducing Risk of Cancer: Multifactorial Ecologic Analysis of Geographic Variation in Age-adjusted Cancer Mortality Rates - Anticancer Research
The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates.
Grant WB, Garland CF.
Anticancer Res. 2006 Jul-Aug;26(4A):2687-99.
PMID: 16886679
CONCLUSION: These results provide additional support for the hypothesis that solar UVB, through photosynthesis of vitamin D, is inversely-associated with cancer mortality rates, and that various other cancer risk-modifying factors do not detract from this link. It is thought that sun avoidance practices after 1980, along with improved cancer treatment, led to reduced associations in the latter period. The results regarding solar UVB should be studied further with additional observational and intervention studies of vitamin D indices and cancer incidence, mortality and survival rates.
Epidemic influenza and vitamin D. - Epidemiol Infect. 2006 Dec;134(6):1129-40. (full text PDF)
Epidemic influenza and vitamin D.
Cannell JJ, Vieth R, Umhau JC, Holick MF, Grant WB, Madronich S, Garland CF, Giovannucci E.
Epidemiol Infect. 2006 Dec;134(6):1129-40. Epub 2006 Sep 7. Review.
PMID: 16959053
New Research by D*action Member Dr. Cedric Garland Suggests Role Low Levels of Vitamin D Play in Cancer Development
San Diego, CA (PRWEB) May 25, 2009 -- Coming on the heels of the publishing in the Annals of Epidemiology of a new study led by Dr. Cedric Garland, on the preventive measures of vitamin D, GrassrootsHealth D*action Project is calling on physicians, health clinics and groups throughout the country to recognize the need for determining vitamin D levels and to ensure the public have their blood levels of vitamin D tested.
According to research from the newly published study by Cedric F. Garland, Dr. P.H., FACE, Department of Family and Preventive Medicine and Moores Cancer Center of the University of California, San Diego (UCSD), "It is projected that raising the minimum year-around serum 25(OH)D level to 40-60 ng/ml (100-150 nmol/L) would prevent approximately 58,000 new cases of breast cancer and 49,000 new cases of colorectal cancer each year, and three quarters of deaths from these diseases, in the US and Canada."
An estimate of cancer mortality rate reductions in Europe and the US with 1,000 IU of oral vitamin D per day. - [Recent Results Cancer Res. 2007] - PubMed Result
An estimate of cancer mortality rate reductions in Europe and the US with 1,000 IU of oral vitamin D per day.
Grant WB, Garland CF, Gorham ED.
Recent Results Cancer Res. 2007;174:225-34. Review.
PMID: 17302200
Vitamin D Deficiency - Treatment and Diagnosis - UCSD-TV - University of California Television - San Diego
Vitamin D Deficiency - Treatment and Diagnosis
Meeting 2: Committee to Review Dietary Reference Intakes for Vitamin D and Calcium - Institute of Medicine
The second committee meeting was held August 4-5, 2009 in Washington, DC and included an Information-Gathering Workshop on August 4, 2009. The agenda for this workshop is below, along with the PowerPoint presentations that were used by the speakers during the workshop.
Please note, online presentations from this meeting are subject to copyright protection. Permission from the speaker is required prior to any copying, reproducing, or rebroadcasting any portion of the speaker's presentations. Additional copyright and legal policies of The National Academies can be read in the National Academies Legal Statement.
The health benefits of vitamin D greatly outweigh the health risks
In his recent essay, Trevor G. Marshall explores how vitamin D supplementation may be contributing to the current epidemics of obesity and chronic disease[1]. Unfortunately, he has overlooked many important papers that disagree with his hypothesis. This letter points out some of the omissions.
The health benefits of vitamin D3 have been reviewed recently[2]. The benefits for bone health have been known for nearly a century. Benefits for cancer, infectious diseases, autoimmune diseases, and metabolic diseases have been identified in the past three decades.
GrassrootsHealth | Vitamin D Action - Seminar - December 2008
Diagnosis and Treatment of Vitamin D Deficiency Seminar
December 2, 2008
Diagnosis & Treatment of Vitamin D Deficiency - Seminar Presentations (PDF Slides) - University of California, San Diego 2008
Diagnosis & Treatment of Vitamin D Deficiency
Wednesday, April 9, 2008 * 12:30pm - 6:00pm
Garren Auditorium, University of California, San Diego
Seminar Presentations
YouTube - Vitamin D and Cancer Prevention
YouTube - Vitamin D and Cancer Prevention. A presentation by Dr. Cedric Garland.
YouTube - Possible 75% cancer mortality reduction with Vitamin D
Possible 75% cancer mortality reduction with Vitamin D Interview with Dr. Cedric Garland
YouTube - Vitamin D and Diabetes-Can We Prevent it?
Vitamin D and Diabetes-Can We Prevent it? Frank C. Garland
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