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16 Dec 09

Vitamin D-induced up-regulation of tumour necrosis factor alpha (TNF-α) in prostate cancer cells - ScienceDirect - Life Sciences

Vitamin D-induced up-regulation of tumour necrosis factor alpha (TNF-alpha) in prostate cancer cells.
Golovko O, Nazarova N, Tuohimaa P.
Life Sci. 2005 Jun 17;77(5):562-77. Epub 2005 Feb 25.
PMID: 15904673
doi:10.1016/j.lfs.2004.10.072

Combined addition of human recombinant TNF-alpha with calcitriol or CB1093 cause enhanced effect in induction of apoptosis. We conclude that under physiological conditions vitamin D activates only the transcription of TNF-alpha gene, for TNF-alpha protein synthesis additional cofactors are required. Therefore a cooperation of vitamin D and TNF-alpha may play an important role in the control of cell growth in prostate cancer.

www.sciencedirect.com/science - Preview

2005 June study research in_vitro vitamin_D vitamin_D-induced up-regulation upregulation TNF-alpha TNF prostate cancer cells prostate_cancer PCa nutrition Tuohimaa apoptosis medline

Calcidiol and prostate cancer - ScienceDirect - The Journal of Steroid Biochemistry and Molecular Biology

Calcidiol and prostate cancer.
Tuohimaa P, Golovko O, Kalueff A, Nazarova N, Qiao S, Syvälä H, Talonpoika R, Lou YR.
J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):183-90. Epub 2005 Jan 22. Review.
PMID: 15860261

www.sciencedirect.com/science - Preview

2005 February study review humans Tuohimaa calcidiol 25ohd vitamin_D prostate cancer prostate_cancer PCa 24-Hydroxylase active hormone nutrition medline Lou

14 Dec 09

Effect of Fish Oil on Heart Rate in Humans: A Meta-Analysis of Randomized Controlled Trials -- Mozaffarian et al. 112 (13): 1945 -- Circulation

Effect of fish oil on heart rate in humans: a meta-analysis of randomized controlled trials.
Mozaffarian D, Geelen A, Brouwer IA, Geleijnse JM, Zock PL, Katan MB.
Circulation. 2005 Sep 27;112(13):1945-52. Epub 2005 Sep 19.
PMID: 16172267
doi: 10.1161/CIRCULATIONAHA.105.556886

Conclusions— In randomized controlled trials in humans, fish oil reduces HR, particularly in those with higher baseline HR or longer treatment duration. These findings provide firm evidence that fish oil consumption directly or indirectly affects cardiac electrophysiology in humans. Po

circ.ahajournals.org/...1945 - Preview

2005 September Circulation study review humans meta-analysis clinical_trials rcts fish_oil omega-3 heart_rate HR heart rate pulse nutrition CVD medline fish oil Mozaffarian

Quantitative Analysis of the Benefits and Risks of Consuming Farmed and Wild Salmon -- Foran et al. 135 (11): 2639 -- Journal of Nutrition

Quantitative analysis of the benefits and risks of consuming farmed and wild salmon.
Foran JA, Good DH, Carpenter DO, Hamilton MC, Knuth BA, Schwager SJ.
J Nutr. 2005 Nov;135(11):2639-43.
PMID: 16251623

Contaminants in farmed Atlantic and wild Pacific salmon raise important questions about the competing health benefits and risks of fish consumption. A benefit-risk analysis was conducted to compare quantitatively the cancer and noncancer risks of exposure to organic contaminants in salmon with the (n-3) fatty acid-associated health benefits of salmon consumption. Recommended levels of (n-3) fatty acid intake, as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may be achieved by consuming farmed or wild salmon while maintaining an acceptable level of noncarcinogenic risk. However, the recommended level of EPA+DHA intake cannot be achieved solely from farmed or wild salmon while maintaining an acceptable level of carcinogenic risk. Although the benefit-risk ratio for carcinogens and noncarcinogens is significantly greater for wild Pacific salmon than for farmed Atlantic salmon as a group, the ratio for some subgroups of farmed salmon is on par with the ratio for wild salmon. This analysis suggests that risk of exposure to contaminants in farmed and wild salmon is partially offset by the fatty acid-associated health benefits. However, young children, women of child-bearing age, pregnant women, and nursing mothers not at significant risk for sudden cardiac death associated with CHD but concerned with health impairments such as reduction in IQ and other cognitive and behavioral effects, can minimize contaminant exposure by choosing the least contaminated wild salmon or by selecting other sources of (n-3) fatty acids.

jn.nutrition.org/...2639 - Preview

2005 November jn study review fish consumption consuming farmed wild salmon benefits risks safety quantitative analysis omega-3 nutrition medline contaminants pollution environmental toxins EPA DHA pollutants

Mercury, Fish Oils, and Risk of Acute Coronary Events and Cardiovascular Disease, Coronary Heart Disease, and All-Cause Mortality in Men in Eastern Finland -- Virtanen et al. 25 (1): 228 -- Arteriosclerosis, Thrombosis, and Vascular Biology

Mercury, fish oils, and risk of acute coronary events and cardiovascular disease, coronary heart disease, and all-cause mortality in men in eastern Finland.
Virtanen JK, Voutilainen S, Rissanen TH, Mursu J, Tuomainen TP, Korhonen MJ, Valkonen VP, Seppänen K, Laukkanen JA, Salonen JT.
Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):228-33. Epub 2004 Nov 11.
PMID: 15539625
doi: 10.1161/01.ATV.0000150040.20950.61

Conclusions— High content of mercury in hair may be a risk factor for acute coronary events and CVD, CHD, and all-cause mortality in middle-aged eastern Finnish men. Mercury may also attenuate the protective effects of fish on cardiovascular health.

Mercury may increase the risk of cardiovascular diseases. In this study, high mercury content in hair increased the risk of cardiovascular morbidity and mortality in middle-aged Finnish men and attenuated the beneficial effects of fish oils on cardiovascular health. Regular consumption of fish with high mercury content should be avoided.

atvb.ahajournals.org/...228 - Preview

2005 January atvb Virtanen study research epidemiological humans Finnish men mercury fish oils all-cause mortality omega-3 DHA nutrition acute coronary events risk middle-aged medline

12 Dec 09

Is Coconut Oil Good for You? - drweil.com

Coconut oil is one of the few saturated fats that doesn't come from animals, but like other saturated fats can raise cholesterol levels and, therefore, should play only a very limited role, if any, in your diet. In the past, it was widely used in movie popcorn, candy bars and commercial baked goods but was phased out of many of them because of consumer opposition to unhealthy tropical oils.

Now coconut oil is being promoted as a weight loss aid; it is also touted in a book by a naturopathic doctor. The rationale goes something like this: as a source of medium-chain triglycerides (MCT), coconut oil isn't stored in the body as fat as readily as oils composed of long-chain triglycerides (LCT). Some research from McGill University in Canada suggests that this is true; MCTs also boost metabolism and satiety, and therefore may promote weight loss when they replace LCTs in the diet. Because they are so easily digested, MCTs are given in hospitals to provide nourishment for critically ill people who have trouble digesting fat.

The benefits of coconut oil in the diet, if any, are likely to be minimal, and until we have more and better evidence about coconut oil's effect of metabolism and potential role in promoting weight loss, I do not recommend using it.

www.drweil.com/QAA316479 - Preview

2005 March drweil info coconut oil coconut_oil nutrition

11 Dec 09

VitD-ez Easy Duration of Vitamin D Synthesis in Human Skin

Vitamin D production in human skin occurs only when UV radiation exceeds a threshold. From simulations of UV irradiances, the VitD-ez www page ( http://zardoz.nilu.no/~olaeng/fastrt/VitD-ez.html) computes the daily duration of dermal vitamin D production at midday when UV radiation exceeds the required threshold. The VitD-ez www page is a simplified version of the more complex VitD web page ( http://zardoz.nilu.no/~olaeng/fastrt/VitD.html). The simplified VitD-ez www page is convenient for users unfamiliar to radiative transfer modelling, because the model input is limited and more intuitive.

zardoz.nilu.no/...VitD-ez.html - Preview

2005 vitamin_D production synthesis skin cutaneous hours calculator tool season latitude date altitude weather clouds time location UVB duration UV radiation Norway Norwegian Engelsen

Daily duration of vitamin D synthesis in human skin with relation to latitude, total ozone, altitude, ground cover, aerosols and cloud thickness - Photochem Photobiol. 2005 Nov-Dec;81(6):1287-90.

Daily duration of vitamin D synthesis in human skin with relation to latitude, total ozone, altitude, ground cover, aerosols and cloud thickness.
Engelsen O, Brustad M, Aksnes L, Lund E.
Photochem Photobiol. 2005 Nov-Dec;81(6):1287-90.
PMID: 16354110

Vitamin D production in human skin occurs only when incident UV radiation exceeds a certain threshold. From simulations of UV irradiances worldwide and throughout the year, we have studied the dependency of the extent and duration of cutaneous vitamin D production in terms of latitude, time, total ozone, clouds, aerosols, surface reflectivity and altitude. For clear atmospheric conditions, no cutaneous vitamin D production occurs at 51 degrees latitude and higher during some periods of the year. At 70 degrees latitude, vitamin D synthesis can be absent for 5 months. Clouds, aerosols and thick ozone events reduce the duration of vitamin D synthesis considerably, and can suppress vitamin D synthesis completely even at the equator. A web page allowing the computation of the duration of cutaneous vitamin D production worldwide throughout the year, for various atmospheric and surface conditions, is available on the Internet at http://zardoz.nilu.no/~olaeng/fastrt/VitD.html and http://zardoz.nilu.no/~olaeng/fastrt/VitD-ez.html. The computational methodology is outlined here.

www.nilu.no/...leverfil.cfm - Preview

2005 November study vitamin_D production synthesis skin cutaneous hours calculator season latitude date altitude weather clouds time location UVB duration medline Norway Norwegian Engelsen UV radiation

08 Dec 09

Vitamin D effective ultraviolet wavelengths due to scattering in shade - ScienceDirect - The Journal of Steroid Biochemistry and Molecular Biology

Vitamin D effective ultraviolet wavelengths due to scattering in shade.
Turnbull DJ, Parisi AV, Kimlin MG.
J Steroid Biochem Mol Biol. 2005 Sep;96(5):431-6. Epub 2005 Jul 6.
PMID: 16005208

www.sciencedirect.com/science - Preview

2005 September study research shade tree umbrella car veranda scattered UV UVB scattering vitamin_D UVA nutrition vitamin_D3 production synthesis medline

D-vitamiinia talteen - Ravinto - HyväTerveys

"Pohjolan kitsas aurinko tarjoaa D-vitamiinia seuraavan kerran maaliskuussa. Talvella luustovitamiinit pitää tankata ruoasta tai purkista. Kala on D-vitamiininlähteistä parhaita.
D on se aurinkovitamiini, jota jokainen muistaa lapsena napsineensa – onnekkaimmat Vitol-helmien tai peräti suklaan muodossa, karskimpien perheiden kasvatit kalanmaksaöljynä.
Ilman D-vitamiinia ihmisen elimistö ei kykene käyttämään hyväkseen ruoasta tulevaa kalsiumia, ja se näkyy luustossa. Riisitauti on puutostautien klassikko, jota tavataan meillä yhä. Joka vuosi siihen sairastuu muutama pikkulapsi, jolle ei ole annettu D-vitamiinilisää.
D-vitamiinin puute pehmentää aikuistenkin luustoa, mutta silloin taudin nimi on osteomalasia. D:n puutteen katsotaan olevan myös yksi osteoporoosin riskitekijöistä.
– D-vitamiinin vajaus ei tunnu olossa eikä näy päälle, ennen kuin luut tosiaan alkavat pehmentyä. Omaa vitamiinitilannettaan kannattaa miettiä, jos ei syö lainkaan kalaa ja käyttää vain vähän D-vitaminoituja maitovalmisteita, toteaa dosentti Christel Lamberg-Allardt Helsingin yliopistosta."

hyvaterveys.fi/...627 - Preview

2005 marraskuu hyvaterveys D-vitamiini kalsium imeytiminen luusto riisitauti osteomalasia osteoporoosi terveys ravitsemus kala Lamberg-Allardt MS syöpä eturauhassyöpä ientulehdus psoriaasi

04 Dec 09

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease - Nutrition & Metabolism | Full text

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease.
Van der Auwera I, Wera S, Van Leuven F, Henderson ST.
Nutr Metab (Lond). 2005 Oct 17;2:28.
PMID: 16229744
doi:10.1186/1743-7075-2-28

CONCLUSION: Previous studies have suggested that diets rich in cholesterol and saturated fats increased the deposition of Abeta and the risk of developing AD. Here we demonstrate that a diet rich in saturated fats and low in carbohydrates can actually reduce levels of Abeta. Therefore, dietary strategies aimed at reducing Abeta levels should take into account interactions of dietary components and the metabolic outcomes, in particular, levels of carbohydrates, total calories, and presence of ketone bodies should be considered.

www.nutritionandmetabolism.com/...28 - Preview

2005 October nutritionandmetabolism study research in_vivo mice Alzheimer's disease Alzheimer's_disease Alzheimer AD ketogenic diet ketogenic_diet low-carbohydrate low-carbohydrate_diet nutrition amyloid beta high-fat high-sfa sfa cholesterol medline

03 Dec 09

Kolesteroli ja pähkinät - sfnet.keskustelu.terveys | Google Groups

Keskustelua kolesterolista, pähkinöistä, probiooteista, maitohappobakteereista yms. sfnet.keskustelu.terveys -ryhmässä 18.11.2005. Mukana mm. Matti Narkia, Juhana Harju, MR2 ja muita.

Osa 2 (viestit 26-50/50)

groups.google.com/...55cb07d68e726bcf - Preview

2005 marraskuu groups.google sfnet.keskustelu.usenet terveys keskustelu ravitsemus kolesteroli pähkinät SVT probiootit maitohappobakteerit Matti Narkia Juhana Harju osa_2

Kolesteroli ja pähkinät - sfnet.keskustelu.terveys | Google Groups

Keskustelua kolesterolista, pähkinöistä, probiooteista, maitohappobakteereista yms. sfnet.keskustelu.terveys -ryhmässä 18.11.2005. Mukana mm. Matti Narkia, Juhana Harju, MR2 ja muita.

Osa 1 (viestit 1-25/50)

groups.google.com/...07f20dce35391fee - Preview

2005 marraskuu groups.google sfnet.keskustelu.usenet terveys keskustelu ravitsemus kolesteroli pähkinät SVT probiootit maitohappobakteerit Matti Narkia Juhana Harju osa_1

30 Nov 09

Egg consumption and endothelial function: a randomized controlled crossover trial

Egg consumption and endothelial function: a randomized controlled crossover trial.
Katz DL, Evans MA, Nawaz H, Njike VY, Chan W, Comerford BP, Hoxley ML.
Int J Cardiol. 2005 Mar 10;99(1):65-70.
PMID: 15721501

Conclusion: Short-term egg consumption does not adversely affect endothelial function in healthy adults, supporting the view that dietary cholesterol may be less detrimental to cardiovascular health than previously thought

www.internationaljournalofcardiology.com/...abstract - Preview

2005 March study research clinical_trial rct humans egg eggs consumption endothelial function endothelial_function endothelium CVD nutrition dietary cholesterol medline flow-mediated vasodilation FMD

29 Nov 09

Cell - Dietary and Genetic Control of Glucose Transporter 2 Glycosylation Promotes Insulin Secretion in Suppressing Diabetes

Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes.
Ohtsubo K, Takamatsu S, Minowa MT, Yoshida A, Takeuchi M, Marth JD.
Cell. 2005 Dec 29;123(7):1307-21.
PMID: 16377570

www.cell.com/...S0092867405011712 - Preview

2005 December cell study research in_vivo animal_study nutrition high-fat diet high-fat_diet type_2 diabetes gene genes enzyme GnT-4a pancreatic beta_cells insulin_resistance insulin resistance medline

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