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There is risk of more tissue reaction following re-establishment of blood supply to tissue temporarily cut off from blood supply. The enzyme Mannan Binding Lectin-Associated Serine Protease-2 (MASP-2) released during re-perfusion of tissue is responsible for triggering a pathway, can be effectively blocked by a molecule that is being tested.
These more sensitive troponin tests have been available since 2008 and are more widely used in Europe than in the US. By lowering the diagnostic threshold, more patients will be referred to specialists and be investigated.
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