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Annals of Medicine: The Way We Age Now | Atul Gawande, MD
Medicine has increased the ranks of the elderly. Can it make old age any easier? The job of any doctor, Bludau later told me, is to support quality of life, by which he meant two things: as much freedom from the ravages of disease as possible, and the retention of enough function for active engagement in the world. Most doctors treat disease, and figure that the rest will take care of itself. And if it doesn’t—if a patient is becoming infirm and heading toward a nursing home—well, that isn’t really a medical problem, is it?
Cachexia and Wasting in the Elderly: Skeletal Muscle Atrophy: Link Between Reduced Protein Synthesis and Increased Protein Degradation: Eley & Tisdale, Journal of Biological Chemistry
Study provides the first evidence of a direct relationship between the depression of protein synthesis in skeletal muscle by PIF and Ang II, through activation of PKR, and eIF2{alpha} phosphorylation, and the enhanced degradation of the myofibrillar protein myosin, through activation of NF-{kappa}B resulting in an increased expression and activity of the ubiquitin-proteasome proteolytic pathway. This suggests that agents that target PKR may be effective in the treatment of muscle atrophy in cancer cachexia or other wasting conditions.
Life and Death in 21st Century Medicine | Improving End-of-Life Care | Videos
Exploring efforts to improve end-of-life medical care through our five-part series, interactive tools and behind-the-scenes videos.
Elder-Care Costs Deplete Savings of a Generation - New York Times
To care for her ailing 97-year-old father over the past three years, Elizabeth Rodriguez, a vice president at the Federal Reserve Bank in New York, has borrowed against her 401(k) retirement plan, sold her house on Staten Island and depleted nearly 20 years of savings.
Fix a Health Problem or Live With It?
New York Times article on the dilemma of deciding whether to follow guidelines and take recommended medications despite debilitating side effects...or live with a disease...especially when you're nearing 90.
Dyslipidemia in Older Adults | Le Jacq | Full-Text Article From The American Journal of Geriatric Cardiology
Jones
IV Iron Added to Epoetin Increases Hemoglobin Response |:| NoBlood |:| Sharon Grant
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Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: a randomized multicenter study.
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