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Evolutionary health promotion - Prev Med. 2002 Feb;34(2):109-18 (free full text PDF file)

Evolutionary health promotion.
Eaton SB, Strassman BI, Nesse RM, Neel JV, Ewald PW, Williams GC, Weder AB, Eaton SB 3rd, Lindeberg S, Konner MJ, Mysterud I, Cordain L.
Prev Med. 2002 Feb;34(2):109-18. Review.
PMID: 11817903
doi:10.1006/pmed.2001.0876

www-personal.umich.edu/...lHlthPromo-PRevention-2002.PDF - Preview

2002 February study review humans Evolutionary health promotion evolution eaton cordain medline nutrition paleolithic diet paleolithic_diet

Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study. - Cardiovasc Diabetol. 2009 Jul 16 (free full text PDF)

Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study.
onsson T, Granfeldt Y, Ahren B, Branell UC, Palsson G, Hansson A, Soderstrom M, Lindeberg S.
Cardiovasc Diabetol. 2009 Jul 16;8(1):35. [Epub ahead of print]
PMID: 19604407
doi:10.1186/1475-2840-8-35

cardiab.com/...1475-2840-8-35.pdf - Preview

2009 July study research clinical_trial rct humans Paleolithic diet Paleolithic_diet type_2 diabetes CVD risk_factors nutrition medline Sweden Lund

An Isoenergetic Very Low Carbohydrate Diet Improves Serum HDL Cholesterol and Triacylglycerol Concentrations, the Total Cholesterol to HDL Cholesterol Ratio and Postprandial Lipemic Responses Compared with a Low Fat Diet in Normal Weight, Normolipidemic W

An isoenergetic very low carbohydrate diet improves serum HDL cholesterol and triacylglycerol concentrations, the total cholesterol to HDL cholesterol ratio and postprandial pipemic responses compared with a low fat diet in normal weight, normolipidemic women.
Volek JS, Sharman MJ, Gómez AL, Scheett TP, Kraemer WJ.
J Nutr. 2003 Sep;133(9):2756-61.
PMID: 12949361

jn.nutrition.org/...2756 - Preview

2003 September jn study research clinical_trial rct humans women postprandial lipemia LDL subclasses inflammation ketogenic_diet very low-carbohydrate_diet very_low-carbohydrate_diet low-carbohydrate diet HDL triglycerides nutrition medline cholesterol

CIMC'2001: A cost-effectiveness study of enteral immune modulating nutrition in intensive care patients

Nevertheless, the development of immunonutrition (IMN), a special form of enteral feed supplemented with specific nutrients (omega-3 fatty acids, arginine, nucleotides and sometimes glutamine) has demonstrated a beneficial effect on patients' immune systems [8]. The advantages of IMN have been demonstrated in a number of studies [9-20]. Two recent meta-analyses have concluded that the use of IMN results in a significant reduction in infection rates, and as a consequence, shorter durations of hospital stay [21-22].

www.uninet.edu/...nutrition - Preview

2001 study review cost-effectiveness enteral immune modulating nutrition IMN intensive care patients ICU omega-3 arginine L-arginine nucleotides glutamine L-glutamine

Effects of n-3 polyunsaturated fatty acids from seal oils on nonalcoholic fatty liver disease associated with hyperlipidemia. - World J Gastroenterol 2008 Nov 7

CONCLUSION: Our results indicate that n-3 PUFA from seal oils is safe and efficacious for patients with NAFLD associated with hyperlipidemia and can improve their total symptom scores, ALT, serum lipid levels and normalization of ultrasonographic evidence. Further study is needed to confirm these results.

Effects of n-3 polyunsaturated fatty acids from seal oils on nonalcoholic fatty liver disease associated with hyperlipidemia.
Zhu FS, Liu S, Chen XM, Huang ZG, Zhang DW.
World J Gastroenterol. 2008 Nov 7;14(41):6395-400.
PMID: 19009658

www.wjgnet.com/...6395.asp - Preview

2008 November study research clinical_trial rct nonalcoholic fatty liver disease NAFLD omega-3 PUFA EPA DHA hyperlipidemia seal_oil nutrition medline treatment NASH

Novel Nonantibiotic Therapies for Pneumonia* — CHEST

Effective host defense against bacterial infection is dependent on the activation and recruitment of phagocytic cells. The initiation, maintenance, and resolution of this inflammatory response in the setting of bacterial pneumonia is dependent on the expression of cytokines. As the complexities of the host-pathogen interaction are further dissected and unraveled, immunologic manipulation of cytokine expression will likely become an important adjuvant therapy in the treatment of serious lung infections.

Novel nonantibiotic therapies for pneumonia: cytokines and host defense.
Nelson S.
Chest. 2001 Feb;119(2 Suppl):419S-425S. Review.
PMID: 11171779
DOI: 10.1378/chest.119.2_suppl.419S

www.chestjournal.org/...419S.long - Preview

2001 February study review pneumonia lungs immunotherapy immune response cytokines G-CSF TNF medline macrophages phagocytic bacteria bacterial LPS IL-8 IL-10 IL-12 neutrophils

Lipoid pneumonia in lung cancer: radiographic and pathological features -- Tamura et al. 28 (8): 492 -- Japanese Journal of Clinical Oncology

Lipoid pneumonia in lung cancer: radiographic and pathological features.
Tamura A, Hebisawa A, Fukushima K, Yotsumoto H, Mori M.
Jpn J Clin Oncol. 1998 Aug;28(8):492-6.
PMID: 9769783

jjco.oxfordjournals.org/...492 - Preview

1998 August study research epidemiological humans patients lung cancer lung_cancer lipoid pneumonia lipoid_pneumonia medline

The ability of fish oil to suppress tumor necrosis factor {alpha} production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes that influence tumor necrosis factor {alpha} production -- Grimble et al. 76 (2): 4

The ability of fish oil to suppress tumor necrosis factor alpha production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes that influence tumor necrosis factor alpha production.
Grimble RF, Howell WM, O'Reilly G, Turner SJ, Markovic O, Hirrell S, East JM, Calder PC.
Am J Clin Nutr. 2002 Aug;76(2):454-9.
PMID: 12145022

www.ajcn.org/...454 - Preview

2002 August ajcn study research epidemiological humans fish_oil TNF TNF-alpha lymphotoxin_alpha genotype inflammation genetics genes PBMCs medline nurtition omega-3

Long-term effects of a very-low-carbohydrate weight loss diet compared with an isocaloric low-fat diet after 12 mo -- Brinkworth et al. 90 (1): 23 -- American Journal of Clinical Nutrition

Long-term effects of a very-low-carbohydrate weight loss diet compared with an isocaloric low-fat diet after 12 mo.
Brinkworth GD, Noakes M, Buckley JD, Keogh JB, Clifton PM.
Am J Clin Nutr. 2009 May 13. [Epub ahead of print]
PMID: 19439458
doi:10.3945/ajcn.2008.27326

www.ajcn.org/...23 - Preview

2009 May ajcn study research clinical_trial rct very-low-carbohydrate diet very low-carbohydrate_diet low-carbohydrate low-fat lof-fat_diet LC LF weight loss isoenergetic medline nutrition triglycerides HDL LDL apolipoprotein_B apoB weight_loss isocaloric

The Pathobiology of Diabetic Complications: A Unifying Mechanism: Introduction

The pathobiology of diabetic complications: a unifying mechanism.
Brownlee M.
Diabetes. 2005 Jun;54(6):1615-25.
PMID: 15919781

t's a great honor to join the exceptional club of Banting Award winners, many of whom were my role models and mentors. In addition, giving the Banting Lecture also has a very personal meaning to me, because without Frederick Banting, I would have died from type 1 diabetes when I was 8 years old. However, it was already apparent at the time I was diagnosed that for too many people like me, Banting's discovery of insulin only allowed them to live just long enough to develop blindness, renal failure, and coronary disease. For example, when I started college, the American Diabetes Association's Diabetes Textbook had this to say to my parents: "The person with type 1 diabetes can be reassured that it is highly likely that he will live at least into his 30s." Not surprisingly, my parents did not find this particularly reassuring.

www.medscape.com/...505648 - Preview

2005 June Medscape study review pathobiology Diabetic Complications Unifying Mechanism diabetes type_1 type_2

The Pathobiology of Diabetic Complications: a unifying mechanism. - Diabetes

The pathobiology of diabetic complications: a unifying mechanism.
Brownlee M.
Diabetes. 2005 Jun;54(6):1615-25.
PMID: 15919781
doi: 10.2337/diabetes.54.6.1615

diabetes.diabetesjournals.org/...1615.long - Preview

2005 June study review pathobiology Diabetic Complications Unifying Mechanism diabetes type_1 type_2 AGE eNOS medline nutrition

Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide - PNAS

Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide.
Nascimento NR, Lessa LM, Kerntopf MR, Sousa CM, Alves RS, Queiroz MG, Price J, Heimark DB, Larner J, Du X, Brownlee M, Gow A, Davis C, Fonteles MC.
Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):218-23. Epub 2005 Dec 22.
PMID: 16373499
doi: 10.1073/pnas.0509779103

www.pnas.org/...218.long - Preview

2006 January PNAS study research in_vivo animal_study rats inositols inositol medline nutrition diabetes type_2 type_1 endothelial:dysfunction NO insulin mimetic d-chiro-inositol CVD

Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes. - SpringerLink - Journal Article

Conclusions/interpretation These results show that the previously demonstrated beneficial effects of these agents on complication-causing pathways in rodent models of diabetic complications also occur in humans with type 1 diabetes.

Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.
Du X, Edelstein D, Brownlee M.
Diabetologia. 2008 Oct;51(10):1930-2. Epub 2008 Jul 29.
PMID: 18663426
DOI: 10.1007/s00125-008-1100-2

www.springerlink.com/...9v72762274164710 - Preview

2008 October Diabetologia study research clinical_trial rct humans benfotiamine type_1 diabetes medline nutrtion AGE alpha-lipoic_acid lipoic_acid ROS supplementation diabetic complications

13 Jun 09

Prognostic and diagnostic value of telomerase in the head and neck cancer - Entrez PubMed

Kuczkowski J, Mikaszewski B, Pawelczykl T.
[Prognostic and diagnostic value of telomerase in the head and neck cancer]
Otolaryngol Pol. 2006;60(5):723-8. Polish.
PMID: 17263245 [PubMed - indexed for MEDLINE]

www.ncbi.nlm.nih.gov/...query.fcgi - Preview

head neck cancer Prognostic diagnostic value telomerase progosis diagnosis medicine medline science study research peer-reviewed oncology imported delicious head_and_neck

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