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Association between 25-hydroxyvitamin D levels and cognitive performance in middle-aged and older European men.\nLee DM, Tajar A, Ulubaev A, Pendleton N, O'Neill TW, O'Connor DB, Bartfai G, Boonen S, Bouillon R, Casanueva FF, Finn JD, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Silman AJ, Vanderschueren D, Wu FC; EMAS study group.\nJ Neurol Neurosurg Psychiatry. 2009 Jul;80(7):722-9. Epub 2009 May 21.\nPMID: 19460797\ndoi:10.1136/jnnp.2008.165720\n\nConclusion: In this study, lower 25(OH)D levels were associated with poorer performance on the DSST. Further research is warranted to determine whether vitamin D sufficiency might have a role in preserving cognitive function in older adults.

jnnp.bmj.com/...722.abstract - Preview

2009 July study research epidemiological humans middle-aged middle-age older old elderly European men vitamin_D 25ohd status cogntion nutrition cognitive performance medline Europe

Don't be the last to know about what's happening with your friends, family or co-workers just because you're away from your computer. You now can subscribe to receive text messages of your friends' status updates directly from their profiles.

Click on the "Subscribe via SMS" link below your friends' profile pictures to get their latest news while you are mobile. You can also comment on your friends' status updates directly from your phone by replying to the text messages you receive. You can even subscribe to mobile updates from the Facebook Pages of your favorite celebrities, public figures, businesses and organizations.

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2009 June Facebook blog blog_article news friend friends friends' Status Updates update Wherever You Are SMS subscribe receive text messages new feature twitter

March 27, 2009 — A significant decrease in serum 25-hydroxyvitamin D (25[OH]D) levels has led to an increase in vitamin D insufficiency in the US population, especially in racial and ethnic groups, according to results of a population-based study reported in the March 23 issue of the Archives of Internal Medicine.

"Vitamin D insufficiency has been associated with increases in cardiovascular disease, cancer, and infection," write Adit A. Ginde, MD, from the Department of Emergency Medicine at the University of Colorado Denver School of Medicine, Aurora, Colorado, and colleagues. "Vitamin D supplementation appears to mitigate the incidence and adverse outcomes of these diseases and may reduce all-cause mortality."

[...]

"These findings have important implications for health disparities and public health," the study authors conclude. "Our data provide additional evidence that current recommendations for vitamin D supplementation (200-600 IU/d) are inadequate to achieve optimal serum 25(OH)D levels in most of the US population." They add that large, randomized controlled trials of higher doses of vitamin D supplementation are needed to evaluate their effect on general health and mortality.

www.medscape.com/...590226 - Preview

2009 March medscape news vitamin D vitamin_D levels level status 25ohd calcidiol decreasing low_levels USA inadequacy insufficiency deficiency prevalence health nutrition mortality recommendations

Why is it that vitamin D deficiency can manifest in so many different ways in different people? One big reason is something called vitamin D receptor (VDR) genotypes, the variation in the receptor for vitamin D.

Why is it that the dose of vitamin D necessary to reach a specific level differs so widely from one person to the next? VDR genotype, again. Variation in blood levels of 25-hydroxy vitamin D from a specific dose of vitamin D can vary three-fold, as shown by a University of Toronto study. In other words, a dose of 4000 units per day may yield a 25-hydroxy vitamin D blood level of 30 ng/ml in Mary, 60 ng/ml in Paul, and 90 ng/ml in Pete--same dose, different blood levels

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2009 March heartscanblog blog_article info vitamin D vitamin_D vitamin_D_receptor_genotype VDR_genotype VDR genotype genetics vitamin_D_receptor nutrition 25OHD calcidiol susceptibility conditions diseases levels status deficiency manifestation manifest

Ecological Studies Of Ultraviolet B, Vitamin D And Cancer Since 2000.
Grant WB, Mohr SB.
Ann Epidemiol. 2009 Mar 6. [Epub ahead of print]
PMID: 19269856
doi:10.1016/j.annepidem.2008.12.014

www.sciencedirect.com/science - Preview

2009 March study review ecological epidemiological vitamin D vitamin_D cancer UVB Grant latitude calcidiol 25ohd colon_cancer colon breast_cancer breast incidence mortality status nutrition medline prevention cancer_prevention

Serum Vitamin D and Risk of Prostate Cancer in a Case-Control Analysis Nested Within the European Prospective Investigation into Cancer and Nutrition (EPIC).
Travis RC, Crowe FL, Allen NE, Appleby PN, Roddam AW, Tjønneland A, Olsen A, Linseisen J, Kaaks R, Boeing H, Kröger J, Trichopoulou A, Dilis V, Trichopoulos D, Vineis P, Palli D, Tumino R, Sieri S, Bueno-de-Mesquita HB, van Duijnhoven FJ, Chirlaque MD, Barricarte A, Larrañaga N, González CA, Argüelles MV, Sánchez MJ, Stattin P, Hallmans G, Khaw KT, Bingham S, Rinaldi S, Slimani N, Jenab M, Riboli E, Key TJ.
Am J Epidemiol. 2009 Apr 9. [Epub ahead of print]
PMID: 19359375
doi:10.1093/aje/kwp022

aje.oxfordjournals.org/...kwp022v1 - Preview

2009 April aje study research epidemiological case-control EPIC Europe humans men vitamin D vitamin_D prostate cancer prostate_cancer PCa 25ohd calcidiol status level levels risk nutrition medline

T-helper/T-regulator lymphocyte ratio as a new immunobiological index to quantify the anticancer immune status in cancer patients.
Brivio F, Fumagalli L, Parolini D, Messina G, Rovelli F, Rescaldani R, Vigore L, Vezzo R, Vaghi M, Di Bella S, Lissoni P.
In Vivo. 2008 Sep-Oct;22(5):647-50.
PMID: 18853761

RESULTS: The mean TH/TR ratio observed in patients with metasytases was significantly lower with respect to that found in both patients without metastases and controls. On the contrary, the absolute mean number of T-reg cells was higher in patients with metastases than in those without, but the difference was not statistically significant. CONCLUSION: The evaluation of T-reg cells in terms of their proportion with respect to T-helper cell total number seems to be more appropriate than the simple measurement of their absolute count, in order to quantify cancer-related immunosuppression. Thus, the TH/TR ratio could represent a useful biological marker to explore the immune status of cancer patients.

www.ncbi.nlm.nih.gov/...18853761 - Preview

2008 September study research clinical_trial humans cancer patients T-helper:T-suppressor T-helper T-suppressor ratio Tregs T-regs T-regulator TH TR CD4 CD8 CD4+ CD4+CD25+ anticancer immune status immunity metastasis anti-cancer medline

Reinehr T, de Sousa G, Alexy U, Kersting M, Andler W.
Vitamin D status and parathyroid hormone in obese children before and after weight loss.
Eur J Endocrinol. 2007 Aug;157(2):225-32.
PMID: 17656603 [PubMed - in process]

eje-online.org/...225 - Preview

status parathyroid hormone obese children weight loss obesity overweight insulin sensitivity resistance health medicine medical medline nutrition study science research peer-reviewed imported delicious vitamin_D

Perez-Lopez FR.

www.ncbi.nlm.nih.gov/...entrez - Preview

Vitamin D musculoskeletal health women muscle strength muscles weakness sarcopenia osteoporosis osteopenia osteomalacia medicine medline nutrition nutritional optimal optimization level status study science peer-reviewed 25(oh)d calcidiol vitamin vitamin_

Wicherts IS, van Schoor NM, Boeke AJ, Visser M, Deeg DJ, Smit J, Knol DL, Lips P.
Vitamin D status predicts physical performance and its decline in older persons.
J Clin Endocrinol Metab. 2007 Jun;92(6):2058-65. Epub 2007 Mar 6.
PMID: 17341569 [PubMed

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Vitamin-D VitaminD status level Physical Performance Decline Older Persons people health fitness elderly old 25(oh)d calcidiol 25-ohd medicine medline nutrition study science peer-reviewed sarcopenia imported delicious vitamin_D

van der Mei IA, Ponsonby AL, Dwyer T, Blizzard L, Taylor BV, Kilpatrick T, Butzkueven H, McMichael AJ.
Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia.
J Neurol. 2007 May;254(5):581-90. Epub 2007 Apr 11.

www.ncbi.nlm.nih.gov/...entrez - Preview

Vitamin-D VitaminD level status multiple sclerosis ms Australia Tasmania deficiency insufficiency inadequacy prevalence medicine medline study science peer-reviewed nutrition imported delicious vitamin_D

Pittas AG, Harris SS, Stark PC, Dawson-Hughes B.
The effects of calcium and vitamin D supplementation on blood glucose and markers of inflammation in nondiabetic adults.
Diabetes Care. 2007 Apr;30(4):980-6. Epub 2007 Feb 2.
PMID: 17277040 [PubMed - in

care.diabetesjournals.org/...980 - Preview

Effects Calcium Vitamin-D VitaminD supplementation Blood Glucose level status Markers Inflammation diabetes impaired fasting IFG medicine medline nutrition rct clinical trial study science peer-reviewed supplements nutritional dietary impor clinical_trial

Houston DK, Cesari M, Ferrucci L, Cherubini A, Maggio D, Bartali B, Johnson MA, Schwartz GG, Kritchevsky SB.
Association between vitamin D status and physical performance: the InCHIANTI study.
J Gerontol A Biol Sci Med Sci. 2007 Apr;62(4):440-6.
PMID:

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Vitamin-D VitaminD Status Physical Performance function fitness sarcopenia 25-ohd 25(oh)d 25ohd medicine medline nutrition health aging old older elderly people study science peer-reviewed imported delicious vitamin_D

Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, Newmark HL, Giovannucci E, Wei M, Holick MF.
Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis.
Am J Prev Med. 2007 Mar;32(3):210-6.
PMID: 17296473 [

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Optimal Vitamin-D VitaminD Status Colorectal Cancer Prevention 25(oh)d 25-ohd 25ohd calcidiol colon colorectalcancer medicine medline nutrition supplementation supplements supplement study meta-analysis science peer-reviewed holick imported delicious vita

25-hydroxyvitamin D levels and the risk of mortality in the general population.
Melamed ML, Michos ED, Post W, Astor B.
Arch Intern Med. 2008 Aug 11;168(15):1629-37.
PMID: 18695076

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2008 August study research epidemiological humans vitamin D vitamin_D status 25ohd calcidiol all-cause mortality all-cause_mortality medline nutrition

Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.\nDobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W.\nArch Intern Med. 2008 Jun 23;168(12):1340-9.\nPMID: 18574092

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2008 June study research epidemiological humans vitamin D vitamin_D status 25ohd calcidiol 1.25-dihydroxyvitamin_D calcitriol level levels low low_levels CVD cardiovascular mortality CVD_mortality all-cause all-cause_mortality nutrition medline

Vitamin D and cardiovascular disease risk.
Michos ED, Melamed ML.
Curr Opin Clin Nutr Metab Care. 2008 Jan;11(1):7-12. Review.
PMID: 18090651

www.ncbi.nlm.nih.gov/...18090651 - Preview

2008 January study review humans vitamin D deficiency vitamin_D vitamin_D_deficiency CVD risk CVD_risk status 25ohd calcidiol low_levels CVD_risk_factor risk_factor hypertension obesity diabetes metabolic_syndrome nutrition medline

Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis.\nHolick MF.\nAm J Clin Nutr. 2004 Mar;79(3):362-71. Review. Erratum in: Am J Clin Nutr. 2004 May;79(5):890.\nPMID: 14985208

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2004 March ajcn study review humans vitamin D status vitamin_D 25ohd calcidiol sunlight cancer bone health bone_health osteoporosis type 1 diabetes type_1_diabetes type_1 prevention nutrition medline CVD CHD Holick

A comparison of vitamin d levels in nondiabetic and diabetic patient populations.\nYoho RM, Frerichs J, Dodson NB, Greenhagan R, Geletta S.\nJ Am Podiatr Med Assoc. 2009 Jan-Feb;99(1):35-41.\nPMID: 19141720

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2009 January study research epidemiological humans vitamin D vitamin_D status levels diabetic nondiabetic comparison 25ohd Calcidiol type_1 type_2 diabetes nutrition medline type_1_diabetes type_2_diabetes

Vitamin D status and its relationship to body fat, final height, and peak bone mass in young women.\nKremer R, Campbell PP, Reinhardt T, Gilsanz V.\nJ Clin Endocrinol Metab. 2009 Jan;94(1):67-73. Epub 2008 Nov 4.\nPMID: 18984659

jcem.endojournals.org/...67 - Preview

2009 January study research epidemiological humans young women vitamin D vitamin_D insufficiency status levels 25ohd calcidiol body fat body_fat height nutrition medline BMD