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Kieran Lamb

Items from 38 people Kieran Lamb follows

Matti Narkia

Western diet triggers genes that cause the body to store more fat

"(NaturalNews) New research published in The Journal of the Federation of American Societies for Experimental Biology (FASEB) has found that the "Western" diet, typically high in sugar and fat, may be responsible for activating genes that signal the body to become fatter. According to scientists, the body's response to high amounts of energy-dense food is to activate the kappa opioid receptor which triggers increased fat storage.

Researchers arrived at this conclusion by conducting an experiment on two groups of mice. One group had its kappa opioid receptors genetically deactivated while the other remained intact. Both groups were fed diets high in fat and sugar for 16 weeks. At the end of 16 weeks, the group with the deactivated receptor remained lean while the control group gained significant weight.

Besides limiting their bodies' ability to store energy-dense food in their fat stores, the mice whose receptors had been deactivated were noted to also have a limited ability to assimilate and store nutrients from the foods they ingested.

Traci Ann Czyzyk-Morgan, one of the study's researchers, indicated that the findings prove the hypothesis long held by many in the scientific community that the kappa opioid receptor may be responsible for causing widespread obesity in Western countries. She and others continue to encourage people to avoid diets high in fat and sugar.
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Matti Narkia

Fructose may promote metabolic syndrome

"(NaturalNews) A research team from the University of Washington (UW) recently published a study in Physiology & Behavior revealing that moderate consumption of fructose- and high fructose corn syrup-sweetened beverages leads to significant alterations of lipid metabolization in the liver. Conducted on rats, the study also noted marked increases in both cholesterol and triglyceride levels in rats that fed on fructose-sweetened beverages.

Fructose is a monosaccharide sugar that is found in various fruits. It is a simple sugar that is often promoted as being a healthy "fruit" sugar, however the reality is that fructose is just one component of the complex sugar composition that occurs naturally in fruit. Most granulated fructose available today, called crystalline fructose, is derived from fructose-enriched corn syrup.

Similarly, high fructose corn syrup is a fructose-enriched form of highly-processed corn syrup that is commonly found in soda, ketchup, candy, dressings, and many other processed foods. The biggest concern about fructose is the fact that, unlike sucrose, it passes undigested through the small intestine where it enters the portal vein and heads directly to the liver. "

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Matti Narkia

Manninen Nutraceuticals: Pharma D3 - Vahva D-vitamiinivalmiste

"Lukuisat tieteelliset tutkimuksen ovat osoittaneet, että valtaosa suomalaisista kärsii D-vitamiinin puutoksesta, joten Manninen Nutraceuticals Oy on lanseerannut oman D-vitamiinivalmisteen. Nimensä mukaisesti Pharma D3 sisältää D3-vitamiini eli kolekalsiferolia, mikä on selvästi D2-vitamiinia eli ergokalsiferolia tehokkaampaa. Pharma D3 valmistetaan GMP- ja HACCP- ja EOFS-sertifioidussa lääketehtaassa. Pharma D3 on kliinisesti ADME-testattu eli imeytyminen (Absorption), jakautuminen (Distribution), aineenvaihdunta (Metabolism) ja erittyminen (Excretion) on kliinisissä tutkimuksissa dokumentoitu.

Suositeltava vuorokausiannos: 1 tabletti vuorokaudessa

Suositeltu vuorokausiannos sisältää:
D3-vitamiini eli kolekalsiferoli 25 mcg (500 %)*
*Vuorokautisen saannin vertailuarvosta"

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Matti Narkia

KARPPAUS KANNATTAA! Vähähiilihydraattisten ruokavalioiden vaikutus aikuisten ylipainoon ja terveyteen pitkällä aikavälillä - Johanna Joutsen ja Heikki Laatikainen

KARPPAUS KANNATTAA!

Vähähiilihydraattisten ruokavalioiden vaikutus
aikuisten ylipainoon ja terveyteen
pitkällä aikavälillä

Johanna Joutsen
Heikki Laatikainen

Opinnäytetyö
Marraskuu 2009

Fysioterapian koulutusohjelma
Hyvinvointiyksikkö

Jyväskylän ammattikorkeakoulu

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Matti Narkia

veteraaniurheilija: Ensimmäinen suomalainen VHH-tutkimus on nähnyt päivänvalon

"Jyväskylän ammattikorkeakoulussa on tehty lajissaan ensimmäinen tutkimus Suomessa paljon keskustelua aiheuttaneesta vähähiilihydraattisesta ruokavaliosta (VHH). Ruokavaliolla oli edullisia vaikutuksia aikuisten ylipainoon ja terveyteen. Vähähiilihydraattisia ruokavalioita (niitä on useita erilaisia) voidaan suositella ylipainoisille henkilöille. Laihdutustulokset olivat erinomaisia.

Fysioterapiaopiskelijat Heikki Laatikainen ja Johanna Joutsen ovat 18.12.2009 julkaisseet tutkimuksensa "KARPPAUS KANNATTAA! : Vähähiilihydraattisten ruokavalioiden vaikutus aikuisten ylipainoon ja terveyteen pitkällä aikavälillä" Jyväskylän ammattikorkeakoulun palvelimella. Voit lukea koko tutkimuksen tästä (PDF-tiedosto"

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Matti Narkia

The Bioavailability of Vitamin D from Fortified Cheeses and Supplements Is Equivalent in Adults -- Wagner et al. 138 (7): 1365 -- Journal of Nutrition

The bioavailability of vitamin D from fortified cheeses and supplements is equivalent in adults.
Wagner D, Sidhom G, Whiting SJ, Rousseau D, Vieth R.
J Nutr. 2008 Jul;138(7):1365-71.
PMID: 18567762

Compared with baseline, serum parathyroid hormone decreased with both fortification (P = 0.003) and supplementation (P = 0.012). These data demonstrate that vitamin D is equally bioavailable from fortified hard cheeses and supplements, making cheese suitable for vitamin D fortification

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Matti Narkia

Bread Fortified with Cholecalciferol Increases the Serum 25-Hydroxyvitamin D Concentration in Women as Effectively as a Cholecalciferol Supplement -- Natri et al. 136 (1): 123 -- Journal of Nutrition

Bread fortified with cholecalciferol increases the serum 25-hydroxyvitamin D concentration in women as effectively as a cholecalciferol supplement.
Natri AM, Salo P, Vikstedt T, Palssa A, Huttunen M, Kärkkäinen MU, Salovaara H, Piironen V, Jakobsen J, Lamberg-Allardt CJ.
J Nutr. 2006 Jan;136(1):123-7.
PMID: 16365070

Both fortified breads increased serum 25-hydroxyvitamin D concentration as effectively as the cholecalciferol supplement. Supplementation or fortification did not affect serum intact parathyroid hormone concentration or urinary calcium excretion. In conclusion, fortified bread is a safe and feasible way to improve vitamin D nutrition.

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Matti Narkia

A randomised comparison of increase in serum 25-hydroxyvitamin D concentration after 4 weeks of daily oral intake of 10 μg cholecalciferol from multivitamin tablets or fish oil capsules in healthy young adults

A randomised comparison of increase in serum 25-hydroxyvitamin D concentration after 4 weeks of daily oral intake of 10 microg cholecalciferol from multivitamin tablets or fish oil capsules in healthy young adults.
Holvik K, Madar AA, Meyer HE, Lofthus CM, Stene LC.
Br J Nutr. 2007 Sep;98(3):620-5. Epub 2007 Apr 24.
PMID: 17456248

We conclude that fish oil capsules and multivitamin tablets containing 10 microg cholecalciferol administered over a 4-week period produced a similar mean increase in s-25(OH)D concentration.

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Matti Narkia

Manninen Nutraceuticals: D-vitamiinitabletti vs. D-vitamiiniöljykapseli

"Kuluttajille on eräillä keskustelufoorumeilla yritelty uskotella, että öljypohjaiset D-vitamiinivalmisteet omaavat paremman biologisen hyväksikäytettävyyden kuin D-vitamiinitabletit, mutta tälle väitteelle ei löydy mitään tukea tieteellisestä kirjallisuudesta.

Norjalaistutkimuksessa verrattiin D3-vitamiinia sisältävät multivitamiinitabletin ja D3-vitamiinia sisältävän kalaöljykapselin vaikutuksia seerumin (veren) 25-OH-D-vitamiinipitoisuuteen (S-25(OH)D). Koehenkilöt saivat neljän viikon ajan 10 mikrogrammaa D3-vitamiinia joko tableteista tai öljykapseleista. Tablettiryhmässä S-25(OH)D-pitoisuus nousi keskimäärin 35,8 nmol/l ja kapseliryhmässä 32,3 nmol/l. "We conclude that fish oil capsules and multivitamin tablets containing 10 microg cholecalciferol administered over a 4-week period produced a similar mean increase in s-25(OH)D concentration", päättelivät tutkijat.

Vuotta aiemmin julkaistussa suomalaistutkimuksessa havaittiin, että D3-vitamiini imeytyy erilaisista leivistä samalla tehokkuudella kuin D-vitamiinivalmisteesta. Kanadalaistutkijat raportoivat juuston osalta samanlaisia tuloksia. Vuonna 2003 jenkkitutkijat totesivat, että "fat is not required for vitamin D to be bioavailable."

Mainittakoon lopuksi, että D3-vitamiinitabletteihin lisätään yleensä D3-vitamiinivalmistetta, jossa on öljy jo valmiina. Ainesosaluetteloissa lukee lähes säännönmukaisesti "D3-vitamiinivalmiste" ja sen jälkeen suluissa pelkkä aktiiviaine eli "kolekalsiferoli" tai "sisältää mm. kolekalsiferolia ja soijaöljyä" tai jotain vastaavaa. Tämä D3-vitamiinivalmiste on sitten ympäröity täyteaineilla, jotka eivät vaikuta D3-vitamiinin imeytymiseen millään tavalla. Tabletti hajoaa hyvin nopeasti maha-suolikanavassa."

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Matti Narkia

Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology - European Journal of Clinical Nutrition - Abstract of article

Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology.
Peterlik M, Cross HS.
Eur J Clin Nutr. 2009 Dec;63(12):1377-86. Epub 2009 Sep 2.
PMID: 19724293
doi:10.1038/ejcn.2009.105

A compromised vitamin D status, characterized by low 25-hydroxyvitamin D (25-(OH)D) serum levels, and a nutritional calcium deficit are widely encountered in European and North American countries, independent of age or gender. Both conditions are linked to the pathogenesis of many degenerative, malignant, inflammatory and metabolic diseases. Studies on tissue-specific expression and activity of vitamin D metabolizing enzymes, 25-(OH)D-1alpha-hydroxylase and 25-(OH)D-24-hydroxylase, and of the extracellular calcium-sensing receptor (CaR) have led to the understanding of how, in non-renal tissues and cellular systems, locally produced 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) and extracellular Ca2+ act jointly as key regulators of cellular proliferation, differentiation and function. Impairment of cooperative signalling from the 1,25-(OH)2D3-activated vitamin D receptor (VDR) and from the CaR in vitamin D and calcium insufficiency causes cellular dysfunction in many organs and biological systems, and, therefore, increases the risk of diseases, particularly of osteoporosis, colorectal and breast cancer, inflammatory bowel disease, insulin-dependent diabetes mellitus type I, metabolic syndrome, diabetes mellitus type II, hypertension and cardiovascular disease. Understanding the underlying molecular and cellular processes provides a rationale for advocating adequate intake of vitamin D and calcium in all populations, thereby preventing many chronic diseases worldwide.

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