Becca Heileman's List: Down Syndrome

• • Congenital heart  disease  
  • Eye problems  
  • Seizure  disorders  
  • Bone, muscle, nerve, or joint  problems
• Congenital
• Congenital
• Congenital
• Congenital
• • Congenital heart  disease
• life expectancy has risen to the mid-50s
• Some common Down syndrome effects may be present at birth; others may not become  evident until adulthood.
• Some people with Down syndrome may experience many of its effects; others only a  few.

  • this is cool
• Common Down syndrome effects can include:
   
   
   
   
  • Thyroid problems  
  • Hearing problems  
  • Congenital heart  disease  
  • Eye problems  
  • Seizure  disorders  
  • Bone, muscle, nerve, or joint  problems  
  • Leukemia and other  cancers  
  • Immune system problems  
  • Developmental delay  
  • Mental retardation  
  • Alzheimer's  disease.

8 more annotations...

• Surplus production of a cancer-suppressing protein may explain in part why  people with Down syndrome seldom get cancer

• People born with Down syndrome have an extra copy of chromosome 21, instead  of the usual two copies — one from each parent. The third chromosome causes  genetic aberrations that result in the mental retardation and telltale physical  traits that define the condition.

• But chromosome 21 carries 231 genes, including some that may well suppress  cancer. In the new study, researchers provide evidence that the protein  encoded by the RCAN1 gene reins in the rampant blood vessel growth that  a tumor needs to thrive. Scientists theorized that having an extra copy of the  gene would result in more protein being made and add to an anticancer  effect.
• people with Down syndrome are only about one-tenth as likely to get a  solid-tumor cancer as are people without the syndrome

2 more annotations...

• LIFE
• LIFE EXPECTANCY FOR PEOPLE WITH DOWN SYNDROME