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nightsurfer on 2009-08-30Role of vitamin D in the pathogenesis of type 2 diabetes mellitus.
Palomer X, González-Clemente JM, Blanco-Vaca F, Mauricio D.
Diabetes Obes Metab. 2008 Mar;10(3):185-97. Review.
Vitamin D deficiency has been shown to alter insulin synthesis and secretion in both humans and animal models. It has been reported that vitamin D deficiency may predispose to glucose intolerance, altered insulin secretion and type 2 diabetes mellitus. Vitamin D replenishment improves glycaemia and insulin secretion in patients with type 2 diabetes with established hypovitaminosis D, thereby suggesting a role for vitamin D in the pathogenesis of type 2 diabetes mellitus.