This link has been bookmarked by 8 people . It was first bookmarked on 24 Oct 2008, by FruFru FourOne.
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23 May 10
Stephanie Hengyounger pple, easier?
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Younger brains have higher amounts of this NR2B subunit which leaves communication channels between brain cells open longer. That is why young people can learn faster than older adults.
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He found that when he over-expressed αCaMKII while a memory was being recalled, that single memory was eliminated.
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a drug that mimics the αCaMKII over expression that researchers accomplished through genetic manipulation. Or, further downstream substrates that αCaMKII acts upon could become possible drug targets.
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06 Nov 08
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25 Oct 08
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Dr. Tsien had already created a mouse that couldn't form memories by eliminating the NMDA receptor, which receives messages from other neurons. He then garnered international acclaim by making "Doogie," a smart mouse in which a subunit of the NMDA receptor is over-expressed. Younger brains have higher amounts of this NR2B subunit which leaves communication channels between brain cells open longer. That is why young people can learn faster than older adults.
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when he over-expressed αCaMKII while a memory was being recalled, that single memory was eliminated.
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To form a memory, the NMDA receptor is activated, which results in the insertion of AMPA receptors into those synapses and subsequent strengthening of the synaptic connections among hundreds of thousands of neurons. Scientists believe that αCaMKII plays an important role in the insertion of AMPA receptors into synapses during learning and subsequent strengthening of connections between neurons to create a memory.
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24 Oct 08
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