ALLHAT: Quick Reference for Health Care Providers - The Diigo Meta page

• 27 Oct 15
  

  Adam Turetzky

  One non drug comp. sponsored statin 1* preventn trial has been completed. ALLHAT lipid, no difference in mortality. https://t.co/O4UnRIYlqB

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• 26 May 08
  

  Douglas Atlas

  ALLHAT study: Quick Reference for Health Care Providers

  hypertension research cardiovascular allhat

  • The ALLHAT hypertension study results indicate that less costly, traditional diuretics are more effective than newer medicines at lowering high blood pressure and preventing some forms of heart disease.
  • ALLHAT demonstrated that chlorthalidone is superior at preventing CVD events compared to each of the treatment drugs studied: calcium channel blocker (amlodipine), ACE inhibitor (lisinopril), and alpha-adrenergic blocker (doxazosin).
  • The chlorthalidone group had slightly better blood pressure control
  • Participants taking amlodipine had a 38 percent increased risk of heart failure compared to those taking chlorthalidone.
  • The lisinopril group had significantly higher risk of stroke (15 percent), heart failure (19%), and angina (11%) compared to the chlorthalidone group
  • The effectiveness of chlorthalidone compared to lisinopril was more remarkable in blacks than in non-blacks.

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