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nightsurfer on 2009-12-14Traditional chinese medicine in treatment of metabolic syndrome.
Yin J, Zhang H, Ye J.
Endocr Metab Immune Disord Drug Targets. 2008 Jun;8(2):99-111. Review.
Berberine from rhizoma coptidis is an oral hypoglycemic agent. It also has anti-obesity and anti-dyslipidemia activities. The action mechanism is related to inhibition of mitochondrial function, stimulation of glycolysis, activation of AMPK pathway, suppression of adipogenesis and induction of low-density lipoprotein (LDL) receptor expression.