"It is time to work together to design and build better and affordable medical instruments to help medical research. Research labs create medical devices but often incomplete that remains within a small group. Sometimes, same ideas are reinvented again in a different lab. Moreover, some labs have ideas but have no means to bring them forward. To address such issues, an open-source medical devices (OSMD) concept was initiated by the Morgridge Institute for Research (MIR) and the University of Wisconsin-Madison with a goal to collaborate among research groups and companies to develop medical technologies that are affordable and available to research groups around the world. It is a forum for free sharing and development of ideas and existing resources in medical devices in an open-source platform. Interested groups contribute to the projects, and the technology is free to use for everybody. The open-source platform is not only for software but also for hardware and necessary management systems. The first OSMD project is to design an open-source integrated micro-CT/PET/RT system for small animals. A small animal platform is not only important for preclinical research but it provides synergies between basic and clinical sciences. In addition, the system is scalable, versatile and cheaper. It has fewer regulatory obstacles. The ultimate goal is to translate and apply the small animal imaging and therapy system design for human use."