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nightsurfer on 2009-12-08Evidence for alteration of the vitamin D-endocrine system in obese subjects.
Bell NH, Epstein S, Greene A, Shary J, Oexmann MJ, Shaw S.
J Clin Invest. 1985 Jul;76(1):370-3.
The results provide evidence that alteration of the vitamin D-endocrine system in obese subjects is characterized by secondary hyperparathyroidism which is associated with enhanced renal tubular reabsorption of calcium and increased circulating 1,25(OH)2D. The reduction of serum 25-OHD in them is attributed to feedback inhibition of hepatic synthesis of the precursor by the increased serum 1,25(OH)2D.