• 07 May 15
  

  astraldo

  Reducción de daños. La paradoja de la cannabis

  cannabis rryd medicinal

  • Harm reduction-the cannabis paradox

       

       

      Robert Melamede
• 11 Nov 14
  

  mptomei_

  cannabis studies mmj endocannabinoids research marijuana harm reduction

• 28 Jan 14
  

  Neal

  HR cannabis

  • evolution does not make moral distinctions in the selection process,  but utilizes a cannabis-based approach to harm reduction in order to promote survival  of the fittest.
  • More specifically, endocannabinoids homeostatically regulate all  body systems (cardiovascular, digestive, endocrine, excretory, immune, nervous, musculo-skeletal,  reproductive). Therefore, the health of each individual is dependant on this system  working appropriately.
  • oday most European countries and Canada have embraced  the idea that society benefits most when drug policy is designed to help people with  drug problems to live better lives rather than to punish them.
  • the recent global trend towards harm reduction  has resulted from the acknowledgement that drug use has been a part of all societies  throughout history and the realization that repressive policies are expensive, ineffective,  and often harmful.
  • The homeostatic action of cannabinoids on so many physiological structures and processes  is the basis for the hypothesis that the endocannabinoid system is nothing less than  a naturally evolved harm reduction system.
  • All life is dependant upon the maintenance of its dynamic  organization through sufficient input of nutrients and removal of wastes.
  • The role of cannabinoids in neurological health and disease goes beyond the prevention  of cell death and regulates neuronal differentiation.
  • Thus cannabinoids are important homeostatic  modulators of the immune system.
  • The use of cannabinoids in the treatment of Parkinson's disease is an example of a  condition where excessive or deficient cannabinoid activity may prove problematic.
  • Although much has been learned about the therapeutic value of cannabinoid agonists  and antagonists in different situations, scientific understanding of how to appropriately  modulate the endocannabinoid pathways remains preliminary, with much remaining to  be learned.
  • Human trials have established that co-administration of cannabinoids  can dramatically lower opioid use and can provide pain relief for neurogenic symptoms  where other treatments have failed [85].
  • despite the fact that cannabis smoke does produce cellular changes that  are viewed as precancerous, a major epidemiological study does not find that cannabis  smoking is associated with tobacco related cancers
  • Thus far, both endo- and exocannabinoids are seen to reduce harm in numerous circumstances.
  • The cannabinoids help to regulate an amazingly  broad range of biochemical events. All of these effects have genetic foundations.  As such, natural genetic/biochemical variation in a population can be expected to  have significant effects on health and behavior. It should be expected that in a population  distribution of cannabinoid levels and sensitivities, as a function of an individual's  health/disease status, some individuals would naturally need to increase their cannabinoid  activity while others would need theirs lowered.
  • Are cannabinoids addictive, is pleasure addictive, or is a low stress state addictive?
  • Cannabinoids control the extinction of painful  memories [119]. What a blessing for those suffering from debilitating or life threatening illnesses:  cannabinoids may help them to forget their misfortune.
  • These results show both positive and negative feedback relationships between the  endocannabinoid and opiate systems. They also suggest that cannabinoids might serve  to reduce the symptoms of opiate withdrawal [124].
  • We must learn to identify individuals who would be negatively  affected by cannabis use; they are the people that an intelligent drug policy would  help to identify and assist. In contrast, our policy criminalizes the majority of  users and further harms them, perhaps psychologically as well as medically, through  its repercussions.
  • Evolution has selected the endocannabinoids to homeostatically regulate numerous biological  phenomena that can be found in every organized system in the body, and to counteract  biochemical imbalances that are characteristic of numerous damaged or diseased states,  in particular those associated with aging.
  • the harmful consequences of cannabis use,  however exaggerated they often appear to be, are likely to represent significant potential  risk for a minority of the population for whom reduced cannabinoid levels might promote  mental stability, fertility or more regulated food consumption.

  18 more annotations...

• 20 Oct 09
  

  Áine MacDermot

  This article examines harm reduction from a novel perspective. Its central thesis is that harm reduction is not only a social concept, but also a biological one. More specifically, evolution does not make moral distinctions in the selection process, but u
  Is appropriate use of #cannabis better than no use? Harm Reduction Journal 2005, 2:17 http://bit.ly/gTl7z8 #marijuana #research #mmot

  research mmot tweeted marijuana cannabis neuroscience medical-marijuana sociology

• 24 Apr 07
  

  marquis
  • Biological science can be more objectively evaluated than social science. The central theme that will be presented in this article is that appropriate cannabis use reduces biological harm caused by biochemical imbalances, particularly those that increase in frequency with age.
  • In essence, it is proposed that the endocannabinoid system, selected by 600 million years of evolution, is a central mediator of biological harm reduction through its homeostatic activities. The social implications of cannabis use will be viewed as emerging from the biological platform.

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