24-week pharmacovigilance study of 4320 patients taking venlafaxine XR found that patients with preexisting hypertension experienced significant decreases in systolic and diastolic BPs; in patients without preexisting elevated BP, systolic BP increased by an average of 0.3 mm Hg and diastolic BP increased by 0.1 mm Hg; these elevations are both within the reference range.17
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