When and how is it used in tendon repair?
This link has been bookmarked by 39 people . It was first bookmarked on 24 Mar 2008, by Matthew Schuler.
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11 Sep 12
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Lee Spievack
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Alan,
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Steven Badylak
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Dr. Anthony Atala
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Emerging from an everyday ink jet printer is the heart of a mouse. Mouse heart cells go into the ink cartridge and are then sprayed down in a heart shaped pattern layer by layer.
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Dr. Shenot
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Dr. Steven Wolf,
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18 Sep 09
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04 May 09
Jonathan KeaneyThe Future Is Here: Regenerative Powder, Ink Jet Heart Cells And Custom-Made Body Parts
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Add Sticky NoteThat powder is a substance made from pig bladders called extracellular matrix. It is a mix of protein and connective tissue surgeons often use to repair tendons and it holds some of the secrets behind the emerging new science of regenerative medicine.
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Badlayk is one of the many scientists who now believe every tissue in the body has cells which are capable of regeneration
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Add Sticky NoteAtala and his team have built, from the cell level up, 18 different types of tissue so far, including muscle tissue, whole organs and the pulsing heart valve of a sheep
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Find out what other tissues have been made
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Emerging from an everyday ink jet printer is the heart of a mouse. Mouse heart cells go into the ink cartridge and are then sprayed down in a heart shaped pattern layer by layer.
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"The cells will differentiate into the two major cells in the bladder wall, the muscle cells and the lining cells," he explained. "It's very much the future, but it's today. We are doing this today."
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Add Sticky NoteIn this clinical trial at Thomas Jefferson Hospital in Philadelphia, Dr. Patrick Shenot is performing a bladder transplant with an organ built with this patient's own cells. In a process developed by Dr. Atala, the patient's cells were grown in a lab, and then seeded on a biodegradable bladder-shaped scaffold.
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Find out more detail on this process
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Dr. Steven Wolf, at the Army Institute of Surgical Research, says the military has invested millions of dollars in regenerative research, hoping to re-grow limbs, lost muscle, even burned skin.
"And it's hard to ignore this guys missing half his skin, this guy's missing his leg," Wolf said. "You start asking the question, is there somebody out there with the technology that can do this for us? -
Add Sticky NoteSeveral different technologies for harnessing regeneration are now in clinical trials around the world. One machine, being tested in Germany, sprays a burn patient's own cells onto a burn, signaling the skin to re-grow.
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How cool is this!
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Badylak is about to implant matrix material - shaped like an esophagus - into patients with throat cancer.
"We fully expect that this material will cause the body to re-form normal esophageal tissue," Badylak said.
And in a clinical trial at the University of Pittsburgh Medical Center, patient Mary Beth Babo is getting her own adult stem cells injected into her heart, in hopes of growing new arteries. Her surgeon is Dr. Joon Lee.
"It's what we consider the Holy Grail of our field for coronary heart disease," Lee said.
The Holy Grail, because if stem cells can re-grow arteries, there's less need for surgery.
"It's a big difference from open heart surgery to this," said Babo. "If people don't have to go through that, this would be the way to go ... if it works." -
And in a clinical trial at the University of Pittsburgh Medical Center, patient Mary Beth Babo is getting her own adult stem cells injected into her heart, in hopes of growing new arteries. Her surgeon is Dr. Joon Lee.
"It's what we consider the Holy Grail of our field for coronary heart disease," Lee said.
The Holy Grail, because if stem cells can re-grow arteries, there's less need for surgery.
"It's a big difference from open heart surgery to this," said Babo. "If people don't have to go through that, this would be the way to go ... if it works." -
Add Sticky NoteTengion believes regeneration will soon revolutionize transplant medicine. Transplant patients, instead of waiting years for a donated organ, will ship cells off to a lab and wait a few weeks to have their own re-grown.
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Find out about his company
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25 Mar 09
Aaron FAThe Future Is Here: Regenerative Powder, Ink Jet Heart Cells And Custom-Made Body Parts.
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31 Oct 08
Talbot PresleyImagine re-growing a severed fingertip, or creating an organ in the lab that can be transplanted into a patient without risk of rejection. Could advances in regenerative medicine change how we heal? Wyatt Andrews reports.
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12 Oct 08
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29 Aug 08
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24 Jun 08
Don P"When people ask me 'what do you do,' we grow tissues and organs," he said. "We are making body parts that we can implant right back into patients."
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07 Jun 08
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01 Apr 08
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27 Mar 08
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26 Mar 08
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<!-- sphereit start -->Imagine re-growing a severed fingertip, or creating an organ in the lab that can be transplanted into a patient without risk of rejection. It sounds like science fiction, but it's not. It's the burgeoning field of regenerative medicine, in which scientists are learning to harness the body's own power to regenerate itself, with astonishing results. Correspondent Wyatt Andrews brings you to the scientific frontier.
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25 Mar 08
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24 Mar 08
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That powder is a substance made from pig bladders called extracellular matrix. It is a mix of protein and connective tissue surgeons often use to repair tendons and it holds some of the secrets behind the emerging new science of regenerative medicine.
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"Somehow the matrix summons the cells and tell them what to do," Badylak explained. "It helps instruct them in terms of where they need to go, how they need to differentiate
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Public Stiky Notes
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