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nightsurfer on 2009-09-25Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis.
Avenell A, Gillespie WJ, Gillespie LD, O'Connell D.
Cochrane Database Syst Rev. 2009 Apr 15;(2):CD000227. Review.
AUTHORS' CONCLUSIONS: Frail older people confined to institutions may sustain fewer hip fractures if given vitamin D with calcium. Vitamin D alone is unlikely to prevent fracture. Overall there is a small but significant increase in gastrointestinal symptoms and renal disease associated with vitamin D or its analogues. Calcitriol is associated with an increased incidence of hypercalcaemia.