Amitriptyline - Wikipedia, the free encyclopedia - The Diigo Meta page

• 06 Apr 14
  

  crimsonite2099
• 

  Chromatic Chick
  • tricyclic antidepressant (TCA)
  • g major depressive disorder (MDD)
  • • Weight gain
     
    • Anticholinergic side effects (it tends to produce more anticholinergic effects than the other TCAs) such as: 
       
      • Constipation
       
      • Xerostomia (dry mouth)
       
      • Mydriasis (dilated pupils)
       
      • Blurred vision
       
      • Urinary hesitancy
       
      • Reduced GI motility
       
      • Anticholinergic delirium (particularly in the elderly and in Parkinson's disease)
  • • Dizziness
     
    • Headache
  • drowsiness
  • sedative, anticholinergic, epileptogenic and pyrexic
  • development of delirium
  • Disulfiram
  • CNS stimulation and arrhythmias
  • Thyroid hormones
  • serotonin-norepinephrine reuptake inhibitor,
  • serotonin transporter and moderate effects on the norepinephrine transporter
  • dopamine transporter and therefore does not affect dopamine reuptake,
  • metabolised to nortriptyline — a more potent and selective norepinephrine reuptake inhibitor —
  • Amitriptyline inhibits sodium channels, L-type calcium channels,

  13 more annotations...

• 08 Feb 14
  

  Joan Weytze

  amitriplyline tricyclic antidepressant drug treatment depression chronic pain migraines nocturnal enuresis overview IBS anticholinergic Parkinson's insomnia tinnitus cough labile affect pseudobulbar affect dyspepsia ADHD

• 08 Dec 12
  

  cdonn3

  Review

  • at least equal efficacy against depression as the newer class of SSRIs
  • depressive symptoms, these types of tricyclics also ease migraines, tension headaches, anxiety attacks and some schizophrenic symptoms. It is also known to reduce aggression
  • ankylosing spondylitis
  • drowsiness and a dry mouth
  • urinary retention
  • increase the risks of both cognitive impairment and death in older people,
  • serotonin-norepinephrine reuptake inhibitor,
  • negligible influence on the dopamine

  6 more annotations...

• 03 May 12
  

  cooperalice
• 16 Nov 11
  

  hyoomen

  complication interaction antidepressant withdrawal

  • The main two side effects that occur from taking amitriptyline are drowsiness and a dry mouth. Other common side effects of using amitriptyline are mostly due to its anticholinergic activity, including: weight gain, changes in appetite, muscle stiffness, nausea, constipation, nervousness, dizziness, blurred vision, urinary retention, insomnia and changes in sexual function. Some rare side effects include seizures, tinnitus, hypotension, mania, psychosis, sleep paralysis, hypnagogia^{[clarification needed]}, hypnopompia^{[clarification needed]}, heart block, arrhythmias, lip and mouth ulcers, extrapyramidal symptoms, depression, tingling pain or numbness in the feet or hands, yellowing of the eyes or skin, pain or difficulty passing urine, confusion, abnormal production of milk in females, breast enlargement in both males and females, fever with increased sweating, and suicidal thoughts.
  • A side effect of many commonly used drugs with such effects appears to be to increase the risks of both cognitive impairment and death in older people
  • Amitriptyline can induce hepatotoxicity.

  1 more annotation...

• 23 Aug 10
  

  Jan McLaughlin

  mom rx

• 23 Jan 10
  

  eonlearning

  medical migraine delicious

• 03 Nov 09
  

  pheonix165

  • [edit]  Side Effects

     

    Common side effects of using amitriptyline are  mostly due to its anticholinergic activity, including: weight  gain, dry mouth, loss of appetite, drowsiness, muscle stiffness, nausea,  constipation, nervousness, dizziness, blurred vision, urinary retention and insomnia. Some rare side effects  include tinnitus, hypotension, mania, psychosis, heart block, arrhythmias, lip and mouth ulcers, extrapyramidal symptoms, depression, and hepatic toxicity.
• 10 May 09
  

  Prakash Ravi

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