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用进废退这个观点最早是由法国生物学家拉马克提出，他在《动物的哲学》中系统地阐述了他的进化学说(被后人称为“拉马克学说”)，提出了两个法则：一个是用进废退；一个是获得性遗传。并认为这两者既是变异产生的原因，又是适应形成的过程。
Darwin
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